[HTML][HTML] A phase 3 trial of pirfenidone in patients with idiopathic pulmonary fibrosis

TE King Jr, WZ Bradford… - New England journal …, 2014 - Mass Medical Soc
Background In two of three phase 3 trials, pirfenidone, an oral antifibrotic therapy, reduced
disease progression, as measured by the decline in forced vital capacity (FVC) or vital …

Prospective, randomized, multicenter, controlled trial of a bioartificial liver in treating acute liver failure

AA Demetriou, RS Brown Jr, RW Busuttil, J Fair… - Annals of …, 2004 - journals.lww.com
Objective: The HepatAssist liver support system is an extracorporeal porcine hepatocyte-
based bioartificial liver (BAL). The safety and efficacy of the BAL were evaluated in a …

Pirfenidone for idiopathic pulmonary fibrosis: analysis of pooled data from three multinational phase 3 trials

PW Noble, C Albera, WZ Bradford… - European …, 2016 - Eur Respiratory Soc
Pirfenidone is an antifibrotic agent that has been evaluated in three multinational phase 3
trials in patients with idiopathic pulmonary fibrosis (IPF). We analysed pooled data from the …

Serum levels of C‐reactive protein in Crohn's disease and ulcerative colitis

EA Fagan, RF Dyck, PN Maton… - European journal of …, 1982 - Wiley Online Library
Prospective measurements were made of serum C‐reactive protein levels and erythrocyte
sedimentation rate in sixty‐four patients with Crohn's disease and fifty with ulcerative colitis …

Effect of continued treatment with pirfenidone following clinically meaningful declines in forced vital capacity: analysis of data from three phase 3 trials in patients with …

SD Nathan, C Albera, WZ Bradford, U Costabel… - Thorax, 2016 - thorax.bmj.com
Background The assessment of treatment response in idiopathic pulmonary fibrosis (IPF) is
complicated by the variable clinical course. We examined the variability in the rate of …

Efficacy of pirfenidone in patients with idiopathic pulmonary fibrosis with more preserved lung function

C Albera, U Costabel, EA Fagan… - European …, 2016 - Eur Respiratory Soc
This post hoc analysis examined the differences in idiopathic pulmonary fibrosis disease
progression and the effects of pirfenidone in patients stratified by more preserved versus …

Serum amyloid-A protein concentration in inflammatory diseases and its relationship to the incidence of reactive systemic amyloidosis

FC De Beer, EA Fagan, GRV Hughes, RK Mallya… - The Lancet, 1982 - Elsevier
Serum amyloid-A protein (SAA) is the putative precursor of amyloid-A (AA) protein which
forms the fibrils in reactive systemic or secondary amyloidosis. By means of a novel …

Safety of pirfenidone in patients with idiopathic pulmonary fibrosis: integrated analysis of cumulative data from 5 clinical trials

L Lancaster, C Albera, WZ Bradford… - BMJ open …, 2016 - bmjopenrespres.bmj.com
Background Pirfenidone is an oral antifibrotic agent that has been shown to reduce the
decline in lung function in patients with idiopathic pulmonary fibrosis (IPF). We performed an …

Fulminant viral hepatitis

EA Fagan, R Williams - British medical bulletin, 1990 - academic.oup.com
Abstract In the United Kingdom and United States of America, fulminant viral hepatitis is due
mainly to sporadic (non-parenteral non-A, non-B hepatitis and hepatitis B whereas that …

Intrahepatic cholestasis of pregnancy

EA Fagan - Clinics in liver disease, 1999 - Elsevier
Intrahepatic cholestasis of pregnancy (IHCP) is the most common liver disorder unique to
pregnancy and is second only to viral hepatitis as a cause of jaundice. 34, 35, 67,117 …