[HTML][HTML] Advances in the development of antiviral strategies against parvovirus B19

E Manaresi, G Gallinella - Viruses, 2019 - mdpi.com
Parvovirus B19 (B19V) is a human pathogenic virus, responsible for an ample range of
clinical manifestations. Infections are usually mild, self-limiting, and controlled by the …

B19 virus genome diversity: epidemiological and clinical correlations

G Gallinella, S Venturoli, E Manaresi, M Musiani… - Journal of clinical …, 2003 - Elsevier
Genetic analysis of parvovirus B19 has been carried out mainly to establish a framework to
track molecular epidemiology of the virus and to correlate sequence variability with different …

Importin α/β-dependent nuclear transport of human parvovirus B19 nonstructural protein 1 is essential for viral replication

G Alvisi, E Manaresi, EM Cross, M Hoad, N Akbari… - Antiviral Research, 2023 - Elsevier
Abstract Human parvovirus B19 (B19V) is a major human pathogen causing a variety of
diseases, characterized by a selective tropism to human progenitor cells in bone marrow. In …

[HTML][HTML] Parvovirus B19 replication and expression in differentiating erythroid progenitor cells

G Bua, E Manaresi, F Bonvicini, G Gallinella - PLoS One, 2016 - journals.plos.org
The pathogenic Parvovirus B19 (B19V) is characterized by a strict adaptation to erythroid
progenitor cells (EPCs), a heterogeneous population of differentiating cells with diverse …

Diagnosis and quantitative evaluation of parvovirus B19 infections by real‐time PCR in the clinical laboratory

E Manaresi, G Gallinella, E Zuffi… - Journal of medical …, 2002 - Wiley Online Library
A real‐time PCR assay was developed for quantitative detection of B19 DNA in clinical
serum samples. The assay was carried out using a LightCycler instrument and product …

Antiviral effect of cidofovir on parvovirus B19 replication

F Bonvicini, G Bua, E Manaresi, G Gallinella - Antiviral Research, 2015 - Elsevier
Abstract Parvovirus B19 (B19V) is a human ssDNA virus responsible for a wide range of
clinical manifestations, still lacking for a specific antiviral therapy. The identification of …

Hydroxyurea inhibits parvovirus B19 replication in erythroid progenitor cells

F Bonvicini, G Bua, I Conti, E Manaresi… - Biochemical …, 2017 - Elsevier
Abstract Parvovirus B19 (B19V) infection is restricted to erythroid progenitor cells (EPCs) of
the human bone marrow, leading to transient arrest of erythropoiesis and severe …

Identification of an immunodominant peptide in the parvovirus B19 VP1 unique region able to elicit a long-lasting immune response in humans

E Zuffi, E Manaresi, G Gallinella, GA Gentilomi… - Viral …, 2001 - liebertpub.com
The immune response against parvovirus B19 is mainly directed against the two structural
proteins, VP1 and VP2. The amino terminal half of the VP1 unique region has been shown …

[HTML][HTML] Non-Permissive Parvovirus B19 Infection: A Reservoir and Questionable Safety Concern in Mesenchymal Stem Cells

G Bua, P Marrazzo, E Manaresi, C Gamberini… - International Journal of …, 2023 - mdpi.com
Mesenchymal stromal/stem cells (MSCs) are multipotent cells with differentiation,
immunoregulatory and regenerative properties. Because of these features, they represent …

Differential IgM response to conformational and linear epitopes of parvovirus B19 VP1 and VP2 structural proteins

E Manaresi, E Zuffi, G Gallinella… - Journal of medical …, 2001 - Wiley Online Library
The IgM immune response against conformational and linear epitopes of B19 structural
proteins VP1 and VP2 was examined in serum samples with a suspect B19 infection to …