PD-L1

A Kythreotou, A Siddique, FA Mauri, M Bower… - Journal of clinical …, 2018 - jcp.bmj.com
Programmed death ligand 1 (PD-L1) is the principal ligand of programmed death 1 (PD-1), a
coinhibitory receptor that can be constitutively expressed or induced in myeloid, lymphoid …

[HTML][HTML] Immune-based therapies for hepatocellular carcinoma

DJ Pinato, N Guerra, P Fessas, R Murphy, T Mineo… - Oncogene, 2020 - nature.com
Hepatocellular carcinoma (HCC) is the third most frequent cause of cancer-related death.
The immune-rich contexture of the HCC microenvironment makes this tumour an appealing …

Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival

G Bellone, C Smirne, FA Mauri, E Tonel… - Cancer Immunology …, 2006 - Springer
Cytokine shedding by tumor cells into the local microenvironment modulates host immune
response, tumor growth, and metastasis. The study aimed to verify the hypothesis that the …

[HTML][HTML] Trans-arterial chemoembolization as a loco-regional inducer of immunogenic cell death in hepatocellular carcinoma: implications for immunotherapy.

DJ Pinato, SM Murray, A Forner, T Kaneko… - … for immunotherapy of …, 2021 - ncbi.nlm.nih.gov
Background Modulation of adaptive immunity may underscore the efficacy of trans-arterial
chemoembolization (TACE). We evaluated the influence of TACE on T-cell function by …

PCNA and Ki67 expression in breast carcinoma: correlations with clinical and biological variables.

E Leonardi, S Girlando, G Serio, FA Mauri… - Journal of clinical …, 1992 - jcp.bmj.com
AIMS: To investigate the expression of two cell cycle related antigens (proliferating cell
nuclear antigen (PCNA) and Ki67 related antigen) in a series of breast cancers; and the …

Doxycycline and HIV infection suppress tuberculosis-induced matrix metalloproteinases

NF Walker, SO Clark, T Oni, N Andreu… - American journal of …, 2012 - atsjournals.org
Rationale: Tuberculosis kills more than 1.5 million people per year, and standard treatment
has remained unchanged for more than 30 years. Tuberculosis (TB) drives matrix …

[HTML][HTML] Inflammation-based prognostic indices in malignant pleural mesothelioma

DJ Pinato, FA Mauri, R Ramakrishnan, L Wahab… - Journal of Thoracic …, 2012 - Elsevier
Introduction Chronic inflammation plays a key role in the pathogenesis of malignant pleural
mesothelioma (MPM) as a result of asbestos exposure. Biomarkers of systemic inflammation …

[HTML][HTML] Prognostic performance of inflammation-based prognostic indices in primary operable non-small cell lung cancer

DJ Pinato, RJ Shiner, MJ Seckl, J Stebbing… - British journal of …, 2014 - nature.com
Background: At least 30% of patients with primary resectable non-small cell lung cancer
(NSCLC) will experience a relapse in their disease within 5 years following definitive …

Pulmonary sarcoidosis: the 'great pretender'

KE Hawtin, ME Roddie, FA Mauri, SJ Copley - Clinical radiology, 2010 - Elsevier
Sarcoidosis has a wide spectrum of appearances within the thorax. This review will discuss
and illustrate the range of pulmonary manifestations on high-resolution computed …

[HTML][HTML] The systemic inflammatory response identifies patients with adverse clinical outcome from immunotherapy in hepatocellular carcinoma

A Muhammed, CAM Fulgenzi, S Dharmapuri, M Pinter… - Cancers, 2021 - mdpi.com
Simple Summary The investigation of predictive and prognostic markers is pivotal in patients
affected by hepatocellular carcinoma treated with immune-checkpoint-inhibitors …