Aims: To evaluate aspects of the current practice of sentinel lymph node (SLN) pathology in
breast cancer via a questionnaire based survey, to recognise major issues that the …

The early phase of the stimulatory effect of aldosterone on sodium reabsorption in renal
epithelia is thought to involve activation of apical sodium channels. However, the genes …

The sgk, an aldosterone-induced gene in mineralocorticoid target cells, regulates the
epithelial sodium channel. Aldosterone increases sodium reabsorption in tight epithelia. The …

Results on the subcellular localization of the mineralocorticoid receptor (MR) have been
controversial. To determine the subcellular distribution and trafficking of the MR in living …

SGK1 is an AGC kinase that regulates the expression of membrane sodium channels in
renal tubular cells in a manner dependent on the metabolic checkpoint kinase complex …

Sentinel lymph node (SLN) biopsy has become the preferred method for the nodal staging of
early breast cancer, but controversy exists regarding its universal use and consequences in …

Characterization of a mouse cortical collecting duct cell line. A cortical collecting duct (CCD)
cell line has been developed from a mouse transgenic for the early region of simian virus 40 …

Autophagy is required in diverse paradigms of lifespan extension, leading to the prevailing
notion that autophagy is beneficial for longevity. However, why autophagy is harmful in …

The serum-and glucocorticoid-induced kinase (sgk) is a serine and threonine kinase that
stimulates amiloride-sensitive sodium transport in Xenopus oocytes. Because aldosterone …

Amiloride-sensitive Na+ channel activity was examined in the cortical collecting ducts of a
mouse line (SGK1−/−) deficient in the serum-and glucocorticoid-dependent protein kinase …