Genome-wide cell-free DNA fragmentation in patients with cancer

S Cristiano, A Leal, J Phallen, J Fiksel, V Adleff… - Nature, 2019 - nature.com
Cell-free DNA in the blood provides a non-invasive diagnostic avenue for patients with
cancer. However, characteristics of the origins and molecular features of cell-free DNA are …

[HTML][HTML] Cell-free circulating (tumor) DNA before surgery as a prognostic factor in non-metastatic colorectal cancer: a systematic review

SJ Schraa, KL van Rooijen, M Koopman, GR Vink… - Cancers, 2022 - mdpi.com
Simple Summary Patients with colorectal cancer without distant metastases are often cured
by surgical tumor resection. Follow-up is needed because of the risk of disease recurrence …

Impulse oscillometry: a measure for airway obstruction

GR Vink, HGM Arets, J van der Laag… - Pediatric …, 2003 - Wiley Online Library
The impulse oscillometry system (IOS) was introduced as a new technique to assess airflow
obstruction in patients who are not able to perform forced breathing maneuvers, eg, subjects …

Two‐color multiplex ligation‐dependent probe amplification: detecting genomic rearrangements in hereditary multiple exostoses

SJ White, GR Vink, M Kriek, W Wuyts… - Human …, 2004 - Wiley Online Library
Genomic deletions and duplications play an important role in the etiology of human disease.
Versatile tests are required to detect these rearrangements, both in research and diagnostic …

Sixty-day mortality of patients with metastatic colorectal cancer randomized to systemic treatment vs primary tumor resection followed by systemic treatment: the …

DEW van der Kruijssen, SG Elias, GR Vink… - JAMA …, 2021 - jamanetwork.com
Importance The role of primary tumor resection (PTR) in synchronous patients with
metastatic colorectal cancer (mCRC) who had unresectable metastases and few or absent …

Intronic variants in BRCA1 and BRCA2 that affect RNA splicing can be reliably selected by splice‐site prediction programs

MPG Vreeswijk, JN Kraan, HM van der Klift… - Human …, 2009 - Wiley Online Library
A large number of sequence variants identified in BRCA1 and BRCA2 cannot be
distinguished as either disease‐causing mutations or neutral variants. These so‐called …

Perceived care and well-being of patients with cancer and matched norm participants in the COVID-19 crisis: results of a survey of participants in the Dutch PROFILES …

LV Van De Poll-Franse, BH De Rooij… - JAMA …, 2021 - jamanetwork.com
Importance As the resolution of the coronavirus disease 2019 (COVID-19) crisis is
unforeseeable, and/or a second wave of infections may arrive in the fall of 2020, it is …

Colorectal cancer incidence, mortality, tumour characteristics, and treatment before and after introduction of the faecal immunochemical testing-based screening …

ECH Breekveldt, I Lansdorp-Vogelaar… - The lancet …, 2022 - thelancet.com
Background In 2014, a population-based colorectal cancer (CRC) screening programme
was stepwise implemented in the Netherlands comprising faecal immunochemical testing …

Informing metastatic colorectal cancer patients by quantifying multiple scenarios for survival time based on real‐life data

PAH Hamers, MAG Elferink, RK Stellato… - … Journal of Cancer, 2021 - Wiley Online Library
Reported median overall survival (mOS) in metastatic colorectal cancer (mCRC) patients
participating in systemic therapy trials has increased to over 30 months. It is uncertain …

[HTML][HTML] Survival of patients with deficient mismatch repair metastatic colorectal cancer in the pre-immunotherapy era

GE Wensink, MAG Elferink, AM May, L Mol… - British journal of …, 2021 - nature.com
Background Metastatic colorectal cancer patients with deficient mismatch repair (dMMR
mCRC) benefit from immunotherapy. Interpretation of the single-arm immunotherapy trials is …