Role of inflammation in HIV-1 disease progression and prognosis
H Ipp, AE Zemlin, RT Erasmus… - Critical reviews in clinical …, 2014 - Taylor & Francis
Inflammation and immune activation have been thrust to center stage in the understanding
of HIV-1 disease pathogenesis and progression. Early work demonstrated that heightened …
of HIV-1 disease pathogenesis and progression. Early work demonstrated that heightened …
The paradox of the immune response in HIV infection: when inflammation becomes harmful
H Ipp, A Zemlin - Clinica chimica acta, 2013 - Elsevier
HIV-infection is associated with ongoing activation of the immune system and persistent
inflammation. These are key driving forces in the loss of CD4+ T cells, progression to AIDS …
inflammation. These are key driving forces in the loss of CD4+ T cells, progression to AIDS …
Platelet leukocyte aggregates and markers of platelet aggregation, immune activation and disease progression in HIV infected treatment naive asymptomatic …
BB Nkambule, G Davison, H Ipp - Journal of thrombosis and thrombolysis, 2015 - Springer
Platelet aggregates play a crucial role in the immune defence mechanism against viruses.
Increased levels of lipopolysaccharide have been reported in human immunodeficiency …
Increased levels of lipopolysaccharide have been reported in human immunodeficiency …
Large unstained cells: a potentially valuable parameter in the assessment of immune activation levels in HIV infection
N Vanker, H Ipp - Acta haematologica, 2014 - karger.com
Introduction: Chronic immune activation is associated with the accelerated progression of
HIV to AIDS; however, affordable markers reflecting this have not yet been determined. The …
HIV to AIDS; however, affordable markers reflecting this have not yet been determined. The …
The evaluation of platelet function in HIV infected, asymptomatic treatment-naïve individuals using flow cytometry
BB Nkambule, GM Davison, H Ipp - Thrombosis Research, 2015 - Elsevier
Introduction Human immunodeficiency virus (HIV) induces inflammation and platelet
activation. People living with HIV are at increased risk of thrombotic events. Activated …
activation. People living with HIV are at increased risk of thrombotic events. Activated …
Serum adenosine deaminase and total immunoglobulin G correlate with markers of immune activation and inversely with CD4 counts in asymptomatic, treatment …
H Ipp, AE Zemlin, RH Glashoff, J van Wyk… - Journal of clinical …, 2013 - Springer
Purpose HIV-infection is characterized by aberrant immune activation and ongoing
inflammation. Markers of inflammation are now recognized to have prognostic value for …
inflammation. Markers of inflammation are now recognized to have prognostic value for …
Serum free light chains in patients with HIV infection: their association with markers of disease severity and antiretroviral use
AE Zemlin, H Ipp, MA Rensburg… - Journal of Clinical …, 2015 - jcp.bmj.com
Aim Serum free light chain measurements are used to follow-up and manage patients with
monoclonal gammopathies, and abnormal ratios are associated with risk of progression in …
monoclonal gammopathies, and abnormal ratios are associated with risk of progression in …
The value of flow cytometry in the measurement of platelet activation and aggregation in human immunodeficiency virus infection
BB Nkambule, G Davison, H Ipp - Platelets, 2015 - Taylor & Francis
Human immunodeficiency deficiency virus (HIV) infection is associated with chronic
inflammation and an increased risk of thrombotic events. Activated platelets (PLTs) play an …
inflammation and an increased risk of thrombotic events. Activated platelets (PLTs) play an …
Serum protein electrophoresis patterns in human immunodeficiency virus-infected individuals not on antiretroviral treatment
AE Zemlin, H Ipp, S Maleka… - Annals of Clinical …, 2015 - journals.sagepub.com
Background B lymphocyte stimulation is described in human immunodeficiency virus (HIV)
infection and results in ongoing immunoglobulin production with abnormal serum protein …
infection and results in ongoing immunoglobulin production with abnormal serum protein …
The use of the full blood count and differential parameters to assess immune activation levels in asymptomatic, untreated HIV infection
N Vanker, H Ipp - South African Medical Journal, 2014 - ajol.info
Background. A feature of HIV/AIDS is chronic immune activation, which results in a number
of complications including inflammationrelated disorders and blood cytopaenias. Immune …
of complications including inflammationrelated disorders and blood cytopaenias. Immune …