Improving adequacy of small biopsy and fine-needle aspiration specimens for molecular testing by next-generation sequencing in patients with lung cancer: a quality …

V Padmanabhan, HB Steinmetz… - … of pathology & …, 2017 - meridian.allenpress.com
Context.—At our medical center, cytopathologists perform rapid on-site evaluation for
specimen adequacy of fine-needle aspiration and touch imprint of needle core biopsy lung …

Small cell neuroendocrine carcinomas of the lung do not harbor high-risk human papillomavirus

CP Hartley, HB Steinmetz, VA Memoli, LJ Tafe - Human Pathology, 2015 - Elsevier
High-risk subtypes of the human papillomavirus (HPV) are known to drive the pathogenesis
of cervical, anogenital, and oropharyngeal squamous cell carcinomas. Recent reports have …

Validation of a solid-phase electrochemical array for genotyping hepatitis C virus

SS Sam, HB Steinmetz, GJ Tsongalis, LJ Tafe… - Experimental and …, 2013 - Elsevier
Hepatitis C viral infection is a major cause of progressive liver disease. HCV genotype is
one of the most significant baseline predictors of response to HCV antiviral therapy. The …

Automated processing of fluorescence in-situ hybridization slides for HER2 testing in breast and gastro-esophageal carcinomas

LJ Tafe, SF Allen, HB Steinmetz, BA Dokus… - Experimental and …, 2014 - Elsevier
Background HER2 fluorescence in-situ hybridization (FISH) is used in breast and gastro-
esophageal carcinoma for determining HER2 gene amplification and patients' eligibility for …

Rapid fluorescence in situ hybridisation (FISH) for HER2 (ERBB2) assessment in breast and gastro-oesophageal cancer

LJ Tafe, HB Steinmetz, SF Allen, BJ Dokus… - Journal of Clinical …, 2015 - jcp.bmj.com
Evaluation of HER2 (ERBB2) gene amplification or protein expression is standard of care in
breast (BR) and advanced stage gastro-oesophageal cancers to identify patients eligible for …

Utility of the Roche Cobas 4800 for detection of high-risk human papillomavirus in formalin-fixed paraffin-embedded oropharyngeal squamous cell carcinoma

JR Pettus, TL Wilson, HB Steinmetz, JA Lefferts… - Experimental and …, 2017 - Elsevier
Clinical laboratories are expected to reliably identify human papilloma virus (HPV)
associated oropharyngeal squamous cell carcinoma (OPSCC) for prognostic and potential …

[HTML][HTML] Evaluation of the cobas 4800 HPV test for detecting high-risk human papilloma-virus in cervical cytology specimens

IW Martin, HB Steinmetz, CL Lefferts, LJ Dumont… - Pathogens, 2012 - mdpi.com
As new platforms for high-risk strains of human papillomavirus (HR HPV) testing are
introduced into the clinical laboratory, it is important to verify their performance and …

Validation of interleukin 28B genotyping assay for clinical use

MA Cervinski, SS Sam, HB Steinmetz, B Wood… - Clinical …, 2014 - Elsevier
Objectives The favorable CC genotype at rs12979860 upstream of the interleukin (IL)-28B
gene is correlated with a greater post-treatment sustained virologic response rate in chronic …

Use of anchored multiplex PCR enrichment for detection of gene fusions in solid tumors by next generation sequencing

DC Green, SJ Deharvengt, FB De Abreu… - The FASEB …, 2017 - Wiley Online Library
Background The known genomic complexities of human cancer are being used to combat
the disease with novel targeted therapies. Next generation sequencing (NGS) technologies …

DNA Genotyping As a Quality Assurance Measure in Surgical Pathology

M Voudouri, HB Steinmetz, GJ Tsongalis… - Forensic …, 2022 - liebertpub.com
A 65-year-old man was referred to our institution for excision of an invasive well-
differentiated squamous cell carcinoma in his left posterior ear groove that had been …