About 20% of all human cancers are caused by chronic infection or chronic inflammatory
states. Recently, a new hypothesis has been proposed for prostate carcinogenesis. It …

Because more and more men are being diagnosed with prostate cancer worldwide,
knowledge about and prevention of this disease is important. Epidemiological studies have …

A systematic review of radiation therapy trials in several tumour types was performed by The
Swedish Council of Technology Assessment in Health Care (SBU). The procedures for …

Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta …

Background Cancers arise from multiple acquired mutations, which presumably occur over
many years. Early stages in cancer development might be present years before cancers …

Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-
wide significance that together explained one-fifth of the heritability for adult height. By …

Artificial intelligence (AI) has shown promise for diagnosing prostate cancer in biopsies.
However, results have been limited to individual studies, lacking validation in multinational …

A genome-wide association study (GWAS) of educational attainment was conducted in a
discovery sample of 101,069 individuals and a replication sample of 25,490. Three …

Despite its high prevalence, very little is known regarding genetic predisposition to prostate
cancer. A genome-wide scan performed in 66 high-risk prostate cancer families has …

Background High rates of overdiagnosis are a critical barrier to organized prostate cancer
screening. Magnetic resonance imaging (MRI) with targeted biopsy has shown the potential …