User profiles for "author:Hiroko Ohgaki"

Hiroko Ohgaki

Dr
Verified email at charite.de
Cited by 75707

[HTML][HTML] The 2007 WHO classification of tumours of the central nervous system

DN Louis, H Ohgaki, OD Wiestler, WK Cavenee… - Acta …, 2007 - Springer
The fourth edition of the World Health Organization (WHO) classification of tumours of the
central nervous system, published in 2007, lists several new entities, including angiocentric …

[HTML][HTML] The 2016 World Health Organization classification of tumors of the central nervous system: a summary

DN Louis, A Perry, G Reifenberger, A Von Deimling… - Acta …, 2016 - Springer
Abstract The 2016 World Health Organization Classification of Tumors of the Central
Nervous System is both a conceptual and practical advance over its 2007 predecessor. For …

Genetic pathways to primary and secondary glioblastoma

H Ohgaki, P Kleihues - The American journal of pathology, 2007 - Elsevier
Glioblastoma is the most frequent and most malignant human brain tumor. The prognosis
remains very poor, with most patients dying within 1 year after diagnosis. Primary and …

Genetic pathways to glioblastoma: a population-based study

H Ohgaki, P Dessen, B Jourde, S Horstmann… - Cancer research, 2004 - AACR
We conducted a population-based study on glioblastomas in the Canton of Zurich,
Switzerland (population, 1.16 million) to determine the frequency of major genetic alterations …

Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas

H Ohgaki, P Kleihues - Journal of Neuropathology & …, 2005 - academic.oup.com
Published data on prognostic and predictive factors in patients with gliomas are largely
based on clinical trials and hospital-based studies. This review summarizes data on …

Epidemiology and etiology of gliomas

H Ohgaki, P Kleihues - Acta neuropathologica, 2005 - Springer
Gliomas of astrocytic, oligodendroglial and ependymal origin account for more than 70% of
all brain tumors. The most frequent (65%) and most malignant histological type is the …

The definition of primary and secondary glioblastoma

H Ohgaki, P Kleihues - Clinical cancer research, 2013 - AACR
Glioblastoma is the most frequent and malignant brain tumor. The vast majority of
glioblastomas (∼ 90%) develop rapidly de novo in elderly patients, without clinical or …

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

T Watanabe, S Nobusawa, P Kleihues… - The American journal of …, 2009 - Elsevier
IDH1 encodes isocitrate dehydrogenase 1, which participates in the citric acid cycle and was
recently reported to be mutated in 12% of glioblastomas. We assessed IDH1 mutations in …

Overexpression of the EGF Receptor and p53 Mutations are Mutually Exclusive in the Evolution of Primary and Secondary Glioblastomas

K Watanabe, O Tachibana, K Sato… - Brain …, 1996 - Wiley Online Library
Glioblastoma multiforme, the most malignant human brain tumor, may develop de nova
(primary glioblastoma) or through progression from low‐grade or anaplastic astrocytoma …

Primary and secondary glioblastomas: from concept to clinical diagnosis

P Kleihues, H Ohgaki - Neuro-oncology, 1999 - academic.oup.com
Glioblastomas may develop de novo (primary glioblastomas) or through progression from
low-grade or anaplastic astrocytomas (secondary glioblastomas). These subtypes of …