Mechanisms of sphingosine 1-phosphate receptor signalling in cancer
S1P is a small bioactive lipid which exerts its effects following binding to a family of five G
protein-coupled receptors, known as S1P 1–5. Following receptor activation, multiple …
protein-coupled receptors, known as S1P 1–5. Following receptor activation, multiple …
A review of inherited cancer syndromes and their relevance to oral squamous cell carcinoma
SS Prime, NS Thakker, M Pring, PG Guest, IC Paterson - Oral oncology, 2001 - Elsevier
This paper examines the genetic defects associated with inherited cancer syndromes and
their relevance to oral cancer. Tumour suppressor genes are now thought of as either …
their relevance to oral cancer. Tumour suppressor genes are now thought of as either …
The opposing roles of NOTCH signalling in head and neck cancer: a mini review
LF Yap, D Lee, ANM Khairuddin, MF Pairan… - Oral …, 2015 - Wiley Online Library
NOTCH signalling can exert oncogenic or tumour suppressive effects in both solid and
haematological malignancies. Similar to T‐cell acute lymphoblastic leukaemia (T‐ALL) …
haematological malignancies. Similar to T‐cell acute lymphoblastic leukaemia (T‐ALL) …
Corticosteroid resistance in chronic asthma.
J Carmichael, IC Paterson, P Diaz, GK Crompton… - Br med j (clin res ed …, 1981 - bmj.com
Fifty-eight patients with chronic asthma in whom airflow obstruction was relieved by
bronchodilator aerosols but not by oral corticosteroids were compared with 58 other chronic …
bronchodilator aerosols but not by oral corticosteroids were compared with 58 other chronic …
[HTML][HTML] Whole-genome profiling of nasopharyngeal carcinoma reveals viral-host co-operation in inflammatory NF-κB activation and immune escape
Interplay between EBV infection and acquired genetic alterations during nasopharyngeal
carcinoma (NPC) development remains vague. Here we report a comprehensive genomic …
carcinoma (NPC) development remains vague. Here we report a comprehensive genomic …
Pangolin genomes and the evolution of mammalian scales and immunity
Pangolins, unique mammals with scales over most of their body, no teeth, poor vision, and
an acute olfactory system, comprise the only placental order (Pholidota) without a whole …
an acute olfactory system, comprise the only placental order (Pholidota) without a whole …
[HTML][HTML] Nickel (II) complex of polyhydroxybenzaldehyde N4-thiosemicarbazone exhibits anti-inflammatory activity by inhibiting NF-κB transactivation
HB Shawish, WY Wong, YL Wong, SW Loh, CY Looi… - PloS one, 2014 - journals.plos.org
Background The biological properties of thiosemicarbazone have been widely reported. The
incorporation of some transition metals such as Fe, Ni and Cu to thiosemicarbazone …
incorporation of some transition metals such as Fe, Ni and Cu to thiosemicarbazone …
Molecular changes in oral cancer may reflect aetiology and ethnic origin
IC Paterson, JW Eveson, SS Prime - European Journal of Cancer Part B …, 1996 - Elsevier
Oral cancer, although uncommon in the Western world, accounts for up to 40% of all
malignancies in parts of India and South East Asia. Recognised aetiological agents of oral …
malignancies in parts of India and South East Asia. Recognised aetiological agents of oral …
[HTML][HTML] A miR-335/COX-2/PTEN axis regulates the secretory phenotype of senescent cancer-associated fibroblasts
TD Kabir, RJ Leigh, H Tasena, M Mellone… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Senescent cancer-associated fibroblasts (CAF) develop a senescence-associated secretory
phenotype (SASP) that is believed to contribute to cancer progression. The mechanisms …
phenotype (SASP) that is believed to contribute to cancer progression. The mechanisms …
Cuticle degrading proteases from insect moulting fluid and culture filtrates of entomopathogenic fungi
RI Samuels, IC Paterson - … and Physiology Part B: Biochemistry and …, 1995 - Elsevier
Insects degrade their own cuticle during moulting, a process which is catalysed by a
complex mixture of enzymes. Entomopathogenic fungi infect the insect host by penetration of …
complex mixture of enzymes. Entomopathogenic fungi infect the insect host by penetration of …