Gal alpha (1, 3) Gal, the major xenoantigen (s) recognised in pigs by human natural antibodies.

MS Sandrin, IF McKenzie - Immunological reviews, 1994 - europepmc.org
The transplantation of pig organs to humans (xenotransplantation) is now receiving serious
consideration because of the shortage of human donors for organ transplants of kidney, liver …

Anti-pig IgM antibodies in human serum react predominantly with Gal (alpha 1-3) Gal epitopes.

MS Sandrin, HA Vaughan… - Proceedings of the …, 1993 - National Acad Sciences
A major problem with pig-to-human-tissue xenograft studies is that humans have natural
antibodies to pig cells; these antibodies would cause hyperacute rejection if pig tissues were …

Antibody and T cell responses of patients with adenocarcinoma immunized with mannan-MUC1 fusion protein.

V Karanikas, LA Hwang, J Pearson… - The Journal of …, 1997 - Am Soc Clin Investig
Mucin 1 (MUC1) is a large complex glycoprotein that is highly expressed in breast cancer,
and as such could be a target for immunotherapy. In mice, human MUC1 is highly …

Oxidative/reductive conjugation of mannan to antigen selects for T1 or T2 immune responses.

V Apostolopoulos, GA Pietersz… - Proceedings of the …, 1995 - National Acad Sciences
The induction of CD8+ cytotoxic T lymphocytes (CTLs) is desirable for immunization against
many diseases, and recombinant-synthetic peptide antigens are now favored agents to use …

[HTML][HTML] Pilot phase III immunotherapy study in early-stage breast cancer patients using oxidized mannan-MUC1 [ISRCTN71711835]

V Apostolopoulos, GA Pietersz, A Tsibanis… - Breast Cancer …, 2006 - Springer
Abstract Introduction Mucin 1 (MUC1) is a high molecular weight glycoprotein
overexpressed on adenocarcinoma cells and is a target for immunotherapy protocols. To …

Pim-1 associates with protein complexes necessary for mitosis

N Bhattacharya, Z Wang, C Davitt, IF McKenzie, P Xing… - Chromosoma, 2002 - Springer
The proto-oncogene pim-1 is a serine/threonine kinase the over-expression of which
promotes lymphoma formation. Neither the normal function of Pim-1 nor the biochemical …

Molecular cloning of a human immunoglobulin G Fc receptor.

ML Hibbs, L Bonadonna, BM Scott… - Proceedings of the …, 1988 - National Acad Sciences
Human IgG Fc receptor (Fc gamma R) cDNA clones were isolated by cross-species
hybridization by probing cDNA libraries with the low-affinity Fc gamma R beta 1 cDNA clone …

MUC1 and breast cancer.

V Apostolopoulos, GA Pietersz… - Current opinion in …, 1999 - europepmc.org
The development of an effective immunotherapeutic approach to cancer is now a major
focus of research, and despite impressive progress over the last 10 years there are still …

Resistance and susceptibility of mice to bacterial infection: genetics of listeriosis

C Cheers, IF McKenzie - Infection and immunity, 1978 - Am Soc Microbiol
A survey of various strains of mice showed distinct differences in resistance or susceptibility
to Listeria monocytogenes. C57B1, related sublines, NZB, and SJL were resistant to Listeria …

B6. CH-2bm12. A new H-2 mutation in the I region in the mouse.

IF McKenzie, GM Morgan, MS Sandrin… - The Journal of …, 1979 - rupress.org
The B6. CH-2bm12 mutant is described and evidence is presented for the mutational site
occurring in the IA subregion. The mutant is of the gain and loss type as bm12 in equilibrium …