User profiles for "author:Ibrahim Kulac"

Ibrahim Kulac

Koc University
Verified email at ku.edu.tr
Cited by 1194

Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer

E Shrestha, JR White, SH Yu, I Kulac… - The Journal of …, 2018 - auajournals.org
Purpose: Studies demonstrating bacterial DNA and cultivable bacteria in urine samples
have challenged the clinical dogma that urine is sterile. Furthermore, studies now indicate …

Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer

GK Hubbard, LN Mutton, M Khalili, RP McMullin… - Cancer research, 2016 - AACR
Genetic instability, a hallmark feature of human cancers including prostatic
adenocarcinomas, is considered a driver of metastasis. Somatic copy number alterations …

Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular …

MC Haffner, C Weier, MM Xu, A Vaghasia… - The Journal of …, 2016 - Wiley Online Library
Prostate cancer often manifests as morphologically distinct tumour foci and is frequently
found adjacent to presumed precursor lesions such as high‐grade prostatic intraepithelial …

[PDF][PDF] Molecular pathology of prostate cancer

I Kulac, MP Roudier, MC Haffner - Surgical Pathology Clinics, 2021 - Elsevier
Molecular profiling studies have shed new light on the complex biology of prostate cancer.
Genomic studies have highlighted that structural rearrangements are among the most …

IL8 expression is associated with prostate cancer aggressiveness and androgen receptor loss in primary and metastatic prostate cancer

JP Maynard, O Ertunc, I Kulac… - Molecular Cancer …, 2020 - AACR
Chronic inflammation and African ancestry are implicated in prostate cancer
aggressiveness, and inflammation-related genes are more highly expressed in prostate …

Should Gleason 6 be labeled as cancer?

I Kulac, MC Haffner, S Yegnasubramanian… - Current opinion in …, 2015 - journals.lww.com
The implications are that by retaining the label of cancer and implementing the recently
proposed concept of prognostic groups, with patients harboring GS6 tumors placed into the …

Molecular pathology of high-grade prostatic intraepithelial neoplasia: challenges and opportunities

L Trabzonlu, I Kulac, Q Zheng… - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
A better understanding of the early stages of prostate cancer initiation, potentially arising
from precursor lesions, may fuel development of powerful approaches for prostate cancer …

A prospective study of chronic inflammation in benign prostate tissue and risk of prostate cancer: linked PCPT and SELECT cohorts

EA Platz, I Kulac, JR Barber, CG Drake, CE Joshu… - … Biomarkers & Prevention, 2017 - AACR
Background: We leveraged two trials to test the hypothesis of an inflammation–prostate
cancer link prospectively in men without indication for biopsy. Methods: Prostate Cancer …

[HTML][HTML] Distribution of childhood skin diseases according to age and gender, a single institution experience

S Özçelik, İ Kulaç, M Yazıcı, E Öcal - Turkish Archives of Pediatrics …, 2018 - ncbi.nlm.nih.gov
Distribution of childhood skin diseases according to age and gender, a single institution
experience - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Low intratumoral mast cells are associated with a higher risk of prostate cancer recurrence

HA Hempel, NS Cuka, I Kulac, JR Barber… - The …, 2017 - Wiley Online Library
BACKGROUND Mast cells are of interest in prostate cancer because they possess both pro‐
and anti‐tumorigenic properties and are present in the tumor microenvironment. We studied …