User profiles for "author:Ibrahim Kulac"
Ibrahim KulacKoc University Verified email at ku.edu.tr Cited by 1194 |
Profiling the urinary microbiome in men with positive versus negative biopsies for prostate cancer
Purpose: Studies demonstrating bacterial DNA and cultivable bacteria in urine samples
have challenged the clinical dogma that urine is sterile. Furthermore, studies now indicate …
have challenged the clinical dogma that urine is sterile. Furthermore, studies now indicate …
Combined MYC Activation and Pten Loss Are Sufficient to Create Genomic Instability and Lethal Metastatic Prostate Cancer
GK Hubbard, LN Mutton, M Khalili, RP McMullin… - Cancer research, 2016 - AACR
Genetic instability, a hallmark feature of human cancers including prostatic
adenocarcinomas, is considered a driver of metastasis. Somatic copy number alterations …
adenocarcinomas, is considered a driver of metastasis. Somatic copy number alterations …
Molecular evidence that invasive adenocarcinoma can mimic prostatic intraepithelial neoplasia (PIN) and intraductal carcinoma through retrograde glandular …
MC Haffner, C Weier, MM Xu, A Vaghasia… - The Journal of …, 2016 - Wiley Online Library
Prostate cancer often manifests as morphologically distinct tumour foci and is frequently
found adjacent to presumed precursor lesions such as high‐grade prostatic intraepithelial …
found adjacent to presumed precursor lesions such as high‐grade prostatic intraepithelial …
[PDF][PDF] Molecular pathology of prostate cancer
I Kulac, MP Roudier, MC Haffner - Surgical Pathology Clinics, 2021 - Elsevier
Molecular profiling studies have shed new light on the complex biology of prostate cancer.
Genomic studies have highlighted that structural rearrangements are among the most …
Genomic studies have highlighted that structural rearrangements are among the most …
IL8 expression is associated with prostate cancer aggressiveness and androgen receptor loss in primary and metastatic prostate cancer
Chronic inflammation and African ancestry are implicated in prostate cancer
aggressiveness, and inflammation-related genes are more highly expressed in prostate …
aggressiveness, and inflammation-related genes are more highly expressed in prostate …
Should Gleason 6 be labeled as cancer?
I Kulac, MC Haffner, S Yegnasubramanian… - Current opinion in …, 2015 - journals.lww.com
The implications are that by retaining the label of cancer and implementing the recently
proposed concept of prognostic groups, with patients harboring GS6 tumors placed into the …
proposed concept of prognostic groups, with patients harboring GS6 tumors placed into the …
Molecular pathology of high-grade prostatic intraepithelial neoplasia: challenges and opportunities
L Trabzonlu, I Kulac, Q Zheng… - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
A better understanding of the early stages of prostate cancer initiation, potentially arising
from precursor lesions, may fuel development of powerful approaches for prostate cancer …
from precursor lesions, may fuel development of powerful approaches for prostate cancer …
A prospective study of chronic inflammation in benign prostate tissue and risk of prostate cancer: linked PCPT and SELECT cohorts
Background: We leveraged two trials to test the hypothesis of an inflammation–prostate
cancer link prospectively in men without indication for biopsy. Methods: Prostate Cancer …
cancer link prospectively in men without indication for biopsy. Methods: Prostate Cancer …
[HTML][HTML] Distribution of childhood skin diseases according to age and gender, a single institution experience
Distribution of childhood skin diseases according to age and gender, a single institution
experience - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …
experience - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …
Low intratumoral mast cells are associated with a higher risk of prostate cancer recurrence
BACKGROUND Mast cells are of interest in prostate cancer because they possess both pro‐
and anti‐tumorigenic properties and are present in the tumor microenvironment. We studied …
and anti‐tumorigenic properties and are present in the tumor microenvironment. We studied …