The role of extracellular spacer regions in the optimal design of chimeric immune receptors: evaluation of four different scFvs and antigens

RD Guest, RE Hawkins, N Kirillova… - Journal of …, 2005 - journals.lww.com
Human peripheral blood lymphocytes can be transduced to express antigen-dependent
CD3ζ chimeric immune receptors (CIRs), which function independently of the T-cell receptor …

The international neuroblastoma risk groups (INRG): a preliminary report

RP Castleberry, J Pritchard, P Ambros… - European Journal of …, 1997 - Elsevier
Beginning in 1986, there have been a series of conferences, sponsored by the William Guy
Forbeck Research Foundation and the Neuroblastoma Society of the United Kingdom, to …

Phase I/II study of iodine 131 metaiodobenzylguanidine in chemoresistant neuroblastoma: a United Kingdom Children's Cancer Study Group investigation.

LS Lashford, IJ Lewis, SL Fielding… - Journal of Clinical …, 1992 - ascopubs.org
PURPOSE The goal of this study was to evaluate the toxicity of iodine 131
metaiodobenzylguanidine (mIBG) in metastatic neuroblastoma. PATIENTS AND METHODS …

Removal of neuroblastoma cells from bone marrow with monoclonal antibodies conjugated to magnetic microspheres

JG Treleaven, J Ugelstad, T Philip, FM Gibson… - The Lancet, 1984 - Elsevier
Monoclonal anibodies bound to polystyrene microspheres containing magnetite have been
used to remove tumour cells from bone marrow destined for autologous transplantation. The …

Determination of cell surface membrane antigens common to both human neuroblastoma and leukemia-lymphoma cell lines by a panel of 38 monoclonal antibodies

T Sugimoto, E Tatsumi, JT Kemshead… - Journal of the …, 1984 - academic.oup.com
The surface membrane antigens of 7 neuroblastoma and 91 leukemia-lymphoma cell lines
were studied with the use of a total of 36 murine monoclonal antibodies (MoAb) primarily …

Human Thy-1: Expression on the cell surface of neuronal and and glial cells

JT Kemshead, MA Ritter, SF Cotmore, MF Greaves - Brain research, 1982 - Elsevier
The Thy-1 antigen is a cell surface glycoprotein found in neural tissue of all mammalian
species so far studied. The distribution and amount of this antigen has been measured on 4 …

L1 adhesion molecule on human lymphocytes and monocytes: expression and involvement in binding to αvβ3 integrin

O Ebeling, A Duczmal, S Aigner… - European journal of …, 1996 - Wiley Online Library
The L1 adhesion molecule is a member of the immunoglobulin (Ig) superfamily initially
identified in the nervous system which contains six Ig‐like domains. Besides the known L1 …

A pilot study of 131I monoclonal antibodies in the therapy of leptomeningeal tumors

LS Lashford, AG Davies, RB Richardson, SP Bourne… - Cancer, 1988 - Wiley Online Library
A pilot study was performed to investigate the toxicity and therapeutic effect of radiolabeled
antibody administered intrathecally in patients with leptomeningeal tumors. Five patients …

Neural cell adhesion molecule (NCAM) is the antigen recognized by monoclonal antibodies of similar specificity in small‐cell lung carcinoma and neuroblastoma

K Patel, SE Moore, G Dickson… - … journal of cancer, 1989 - Wiley Online Library
We describe reagents from 2 workshops which had been identified as recognizing the same
or very similar antigens based on their tissue reactivity. Examination of their tissue specificity …

Meta‐Iodobenzylguanidine (mIBG) uptake and storage in the human neuroblastoma cell line SK‐N‐BE(2C)

LS Lashford, JP Hancock… - International journal of …, 1991 - Wiley Online Library
Whilst many human neuroblastoma cell lines have been studied to see if they are capable of
taking up mIBG, few appear to have this ability. This contrasts markedly to the situation in …