SUMMARY A cascade of three protein kinases known as a mitogen-activated protein kinase
(MAPK) cascade is commonly found as part of the signaling pathways in eukaryotic cells …

Alcohol dehydrogenases (ADHs) constitute a large family of enzymes responsible for the
reversible oxidation of alcohols to aldehydes with the concomitant reduction of NAD+ or …

The yeast Saccharomyces cerevisiae responds to osmotic stress, ie, an increase in
osmolality of the growth medium, by enhanced production and intracellular accumulation of …

Iron is an absolute requirement for both the host and most pathogens alike and is needed for
normal cellular growth. The acquisition of iron by biological systems is regulated to …

The accumulation of compatible solutes, such as glycerol, in the yeast Saccharomyces
cerevisiae, is a ubiquitous mechanism in cellular osmoregulation. Here, we demonstrate that …

Micro-organisms have developed systems to adapt to sudden changes in the environment.
Here we describe the response of the yeast Saccharomyces cerevisiae to osmotic stress. A …

Yeast cells respond to a shift to higher osmolarity by increasing the cellular content of the
osmolyte glycerol. This response is accompanied by a stimulation of the expression of …

Candida albicans is commonly found in mixed infections with Pseudomonas aeruginosa,
especially in the lungs of cystic fibrosis (CF) patients. Both of these opportunistic pathogens …

The physiological role and possible functional substitution of each of the five alcohol
dehydrogenase (Adh) isozymes in Saccharomyces cerevisiae were investigated in five …

Following the discovery of the first Eukarya in the deep subsurface, intense interest has
developed to understand the diversity of eukaryotes living in these extreme environments …