Conventional immunohistochemistry (IHC) is a widely used diagnostic technique in tissue
pathology. However, this technique is associated with a number of limitations, including high …

Various forms of immunotherapy, such as checkpoint blockade immunotherapy, are proving
to be effective at restoring T cell-mediated immune responses that can lead to marked and …

Epstein–Barr virus (EBV) is a ubiquitous oncovirus associated with specific epithelial and
lymphoid cancers. Among the epithelial cancers, nasopharyngeal carcinoma (NPC) …

Objective The nature of the tumour-infiltrating leucocytes (TILs) is known to impact clinical
outcome in carcinomas, including hepatocellular carcinoma (HCC). However, the role of …

Simple Summary In recent years, immunotherapy has emerged as a pillar in the fight against
cancer. However, the heterogeneity within the tumor microenvironment poses challenges to …

Lung cancer is the world's leading cause of cancer death and shows strong ancestry
disparities. By sequencing and assembling a large genomic and transcriptomic dataset of …

Background and aims Chronic inflammation induced by chronic hepatitis B virus (HBV)
infection increases the risk of hepatocellular carcinoma (HCC). However, little is known …

We read with great interest the article published by Zuo et al, which highlighted the presence
of SARS-CoV-2 RNA in stool samples during active and convalescence phases of COVID …

ABSTRACT Programmed death one (PD-1) is a well-established co-inhibitory regulator that
suppresses proliferation and cytokine production of T cells. Despite remarkable progress in …

Hepatocellular carcinoma (HCC) often develops following chronic hepatitis B virus (HBV)
infection and responds poorly to immune checkpoint blockade. Here, we examined the …