Glycosaminoglycan‐protein interactions: definition of consensus sites in glycosaminoglycan binding proteins
RE Hileman, JR Fromm, JM Weiler, RJ Linhardt - Bioessays, 1998 - Wiley Online Library
Although interactions of proteins with glycosaminoglycans (GAGs), such as heparin and
heparan sulphate, are of great biological importance, structural requirements for protein …
heparan sulphate, are of great biological importance, structural requirements for protein …
Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate
Y Chen, T Maguire, RE Hileman, JR Fromm, JD Esko… - Nature medicine, 1997 - nature.com
Dengue virus is a human pathogen that has reemerged as an increasingly important public
health threat. We found that the cellular receptor utilized by dengue envelope protein to bind …
health threat. We found that the cellular receptor utilized by dengue envelope protein to bind …
High-throughput sequencing detects minimal residual disease in acute T lymphoblastic leukemia
D Wu, A Sherwood, JR Fromm, SS Winter… - Science translational …, 2012 - science.org
High-throughput sequencing (HTS) of lymphoid receptor genes is an emerging technology
that can comprehensively assess the diversity of the immune system. Here, we applied HTS …
that can comprehensively assess the diversity of the immune system. Here, we applied HTS …
Structural differences and the presence of unsubstituted amino groups in heparan sulphates from different tissues and species
T Toida, H Yoshida, H Toyoda, I Koshiishi… - Biochemical …, 1997 - portlandpress.com
This study presents a comparison of heparan sulphate chains isolated from various porcine
and bovine tissues. 1H-NMR spectroscopy (500 MHz) was applied for structural and …
and bovine tissues. 1H-NMR spectroscopy (500 MHz) was applied for structural and …
CAR T-cell therapy is effective for CD19-dim B-lymphoblastic leukemia but is impacted by prior blinatumomab therapy
V Pillai, K Muralidharan, W Meng, A Bagashev… - Blood …, 2019 - ashpublications.org
Tisagenlecleucel, a chimeric antigen receptor (CAR) T-cell product targeting CD19 is
approved for relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL). However, the …
approved for relapsed/refractory B-cell acute lymphoblastic leukemia (B-ALL). However, the …
“Blasts” in myeloid neoplasms–how do we define blasts and how do we incorporate them into diagnostic schema moving forward?
We document blast percentage in every bone marrow report, and it influences the diagnosis
and classification of hematopoietic neoplasms and subsequent management of patients …
and classification of hematopoietic neoplasms and subsequent management of patients …
A phase II trial of pembrolizumab and vorinostat in recurrent metastatic head and neck squamous cell carcinomas and salivary gland cancer
CP Rodriguez, Q Wu, J Voutsinas, JR Fromm… - Clinical Cancer …, 2020 - AACR
Purpose: This clinical trial combined pembrolizumab and vorinostat in recurrent/metastatic
squamous cell carcinomas of the head and neck (HN), and salivary gland cancer (SGC) …
squamous cell carcinomas of the head and neck (HN), and salivary gland cancer (SGC) …
Mass cytometry of Hodgkin lymphoma reveals a CD4+ regulatory T-cell–rich and exhausted T-effector microenvironment
FZ Cader, RCJ Schackmann, X Hu… - Blood, The Journal …, 2018 - ashpublications.org
In classical Hodgkin lymphoma (cHL), the host antitumor immune response is ineffective.
Hodgkin Reed-Sternberg (HRS) cells have multifaceted mechanisms to evade the immune …
Hodgkin Reed-Sternberg (HRS) cells have multifaceted mechanisms to evade the immune …
Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion
Classical Hodgkin lymphoma (cHL) is composed of rare malignant Hodgkin Reed-Sternberg
(HRS) cells within an extensive, but ineffective, inflammatory/immune cell infiltrate. HRS …
(HRS) cells within an extensive, but ineffective, inflammatory/immune cell infiltrate. HRS …
Nature of the interaction of heparin with acidic fibroblast growth factor
H Mach, DB Volkin, CJ Burke, CR Middaugh… - Biochemistry, 1993 - ACS Publications
Revised Manuscript Received February 9, 1993 abstract: The binding of human acidic
fibroblast growth factor (aFGF) to heparin has been analyzed by a variety of different …
fibroblast growth factor (aFGF) to heparin has been analyzed by a variety of different …