Objective To analyze the potential variability in rates of circumferential resection margin
(CRM) involvement between different surgeons and time periods and to determine the …

Objectives: Examine the cause of local recurrence (LR) and patient survival (S) following
abdominoperineal resection (APR) and anterior resection (AR) for rectal carcinoma and the …

Background Present clinical algorithms assign adjuvant chemotherapy according to
prognosis, but clinical decisionmaking would be greatly improved if reliable predictive …

The development and standardisation of an inventory for measuring anti-epileptic drug
effects on cognition and affect is described. The Side Effect and Life Satisfaction inventory …

BACKGROUND: A murine monoclonal antibody against the 17-1A epithelial antigen has
been shown to be a useful adjuvant therapy in colorectal cancer. Its clinical use could be …

Raman mapping has been used to determine the subcellular distribution of two substituted
zinc phthalocyanines designed for use as photosensitizers in photodynamic therapy. Each …

A patient with the unusual post mortem finding of myocardial metastatic carcinoid tumour
without classical valvular or endocardial carcinoid disease is described. This rare …

Photodynamic therapy (PDT) is a developing method for the treatment of cancer, relying
upon the activation of a photosensitive drug by light, in order to selectively destroy target …

According to latest figures there are approximately 8500 new diagnoses of rectal cancer in
England and Wales each year (Office for National Statistics, 1999, personal communication) …