A Functional Interleukin-1 Receptor Antagonist Polymorphism Influences Atherosclerosis Development The Interleukin-1β: Interleukin-1 Receptor Antagonist Balance …

PS Olofsson, Y Sheikine, K Jatta, M Ghaderi… - Circulation …, 2009 - jstage.jst.go.jp
Background: Interleukin (IL)-β plays a central role in inflammation and atherosclerosis, but
levels of IL-1β, its natural antagonist, IL-1Ra, and their balance in human atherosclerotic …

[HTML][HTML] Clinical Routine TERT Promoter Mutational Screening of Follicular Thyroid Tumors of Uncertain Malignant Potential (FT-UMPs): A Useful Predictor of …

M Hysek, JO Paulsson, K Jatta, I Shabo, A Stenman… - Cancers, 2019 - mdpi.com
Mutations of the Telomerase reverse transcriptase (TERT) gene promoter are recurrently
found in follicular thyroid carcinoma (FTC) and follicular tumors of uncertain malignant …

The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents

PS Olofsson, K Jatta, D Wagsater… - … , and vascular biology, 2005 - Am Heart Assoc
Objective—Inflammatory processes play an important role in atherosclerosis, and increasing
evidence implies that microbial pathogens and proinflammatory cytokines are involved in …

Overexpression of von Hippel-Lindau protein in skeletal muscles of patients with chronic obstructive pulmonary disease

K Jatta, G Eliason, GM Portela-Gomes… - Journal of clinical …, 2009 - jcp.bmj.com
Background: A significant number of patients with chronic obstructive pulmonary disease
(COPD) exhibit skeletal muscle wasting and decreased capillary area formation, which …

miR-100-5p confers resistance to ALK tyrosine kinase inhibitors Crizotinib and Lorlatinib in EML4-ALK positive NSCLC

Y Lai, M Kacal, M Kanony, I Stukan, K Jatta… - Biochemical and …, 2019 - Elsevier
Lung cancer causes the highest number of cancer-related deaths worldwide. Resistance to
therapy is a major clinical issue contributing to the poor prognosis of lung cancer. In recent …

MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency

…, C Tortoioli, A Brozzetti, K Jatta… - The Journal of …, 2006 - academic.oup.com
Context: The polymorphism of class II HLA genes modulates the genetic risk for several
endocrine autoimmune diseases. The constitutive class II expression on antigen-presenting …

[HTML][HTML] TERT Promoter Mutation Spatial Heterogeneity in a Metastatic Follicular Thyroid Carcinoma: Implications for Clinical Work-Up

A Stenman, M Hysek, K Jatta, R Bränström… - Endocrine …, 2019 - Springer
Follicular thyroid carcinoma (FTC) is not routinely diagnosed by a preoperative fine needle
aspiration biopsy (FNAB), and the final diagnosis relies on histopathological criteria visible …

Digital droplet PCR TERT promoter mutational screening in fine needle aspiration cytology of thyroid lesions: A highly specific technique for pre‐operative …

…, C Larsson, J Zedenius, K Jatta… - Diagnostic …, 2023 - Wiley Online Library
Background Despite the advent of comprehensive molecular testing in surgical pathology,
most centers still rely on the morphological assessment of fine‐needle aspiration cytology …

[HTML][HTML] Spatial distribution patterns of clinically relevant TERT promoter mutations in follicular thyroid tumors of uncertain malignant potential: advantages of the digital …

M Hysek, K Jatta, LS Hellgren, A Stenman… - The Journal of Molecular …, 2021 - Elsevier
In thyroid carcinomas, telomerase reverse transcriptase (TERT) promoter mutations C228T
and C250T predict an unfavorable clinical outcome. The analysis is particularly valuable …

[HTML][HTML] Establishment and characterization of a novel breast implant-associated anaplastic large cell lymphoma cell line and PDX model (BIA-XR1) with a unique …

…, R D'Aulerio, M He, A Ketscher, K Jatta… - Current Research in …, 2023 - Elsevier
Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is an uncommon T-
cell lymphoma type with distinct clinical, molecular and genetic features. Establishment of …