Since the Oxford Classification of IgA nephropathy (IgAN) was published in 2009, MEST
scores have been increasingly used in clinical practice. Further retrospective cohort studies …

Although pathologic classifications exist for several renal diseases, including IgA
nephropathy, focal segmental glomerulosclerosis, and lupus nephritis, a uniform …

IgA nephropathy is the most common glomerular disease worldwide, yet there is no
international consensus for its pathological or clinical classification. Here a new …

Summary Tyrosine kinase 2 (Tyk2) is a nonreceptor tyrosine kinase that belongs to the
Janus kinase (Jak) family. Here we identified a homozygous Tyk2 mutation in a patient who …

Pathological classifications in current use for the assessment of glomerular disease have
been typically opinion-based and built on the expert assumptions of renal pathologists about …

Results The validation study showed that kidney failure at 10-year follow-up was
significantly different between the histopathologic classes (P< 0.001). Kidney failure at 10 …

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is the most common
cause of rapidly progressive glomerulonephritis worldwide, and the renal biopsy is the gold …

We present a consensus report pertaining to the improved clarity of definitions and
classification of glomerular lesions in lupus nephritis that derived from a meeting of 18 …

The human UBE3A gene shows brain-specific partial imprinting, and lack of a maternally
inherited allele causes Angelman syndrome (AS), which is characterized by …

Over 10 years have passed since the latest revision of the histopathologic classification of
lupus nephritis. This revision was a significant improvement compared with the previous …