Green tea: cancer preventive beverage and/or drug

H Fujiki, M Suganuma, K Imai, K Nakachi - Cancer letters, 2002 - Elsevier
Green tea and (−)-epigallocatechin gallate (EGCG) are now acknowledged cancer
preventives in Japan and has made it possible for us to establish the concept of a cancer …

A new function of green tea: prevention of lifestyle‐related diseases

…, S Matsuyama, K Imai, K Nakachi… - Annals of the New …, 2001 - Wiley Online Library
In the normal human life span, there occur lifestyle‐related diseases that may be
preventable with nontoxic agents. This paper deals with the preventive activity of green tea …

The CYP1A1 gene and cancer susceptibility

K name Kawajiri, KI Nakachi, K zue Imai… - Critical reviews in …, 1993 - Elsevier
A close correlation between cigarette smoking associated lung cancer incidence and an
Msp I restriction fragment length polymorphism (RFLP) of the human P-450 1A1 (CYP1A1) …

Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population

K Imai, S Matsuyama, S Miyake, K Suga, K Nakachi - The lancet, 2000 - thelancet.com
Background One of the most critical questions in immunosurveillance is whether differences
between individuals with regards to natural immunological host defence can predict future …

[HTML][HTML] Gemcitabine alone or in combination with cisplatin in patients with biliary tract cancer: a comparative multicentre study in Japan

T Okusaka, K Nakachi, A Fukutomi, N Mizuno… - British journal of …, 2010 - nature.com
Background: A British randomised study of gemcitabine plus cisplatin (GC) combination
showed promising results in biliary tract cancer (BTC) patients. In our study, we evaluated …

Phase III study of sorafenib after transarterial chemoembolisation in Japanese and Korean patients with unresectable hepatocellular carcinoma

M Kudo, K Imanaka, N Chida, K Nakachi… - European journal of …, 2011 - Elsevier
BACKGROUND: In Japan and South Korea, transarterial chemoembolisation (TACE) is an
important locoregional treatment for patients with unresectable hepatocellular carcinoma …

Cross sectional study of effects of drinking green tea on cardiovascular and liver diseases

K Imai, K Nakachi - Bmj, 1995 - bmj.com
Objective: To investigate the association between consumption of green tea and various
serum markers in a Japanese population, with special reference to preventive effects of …

Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene

K Kawajiri, K Nakachi, K Imai, A Yoshii… - Febs …, 1990 - Wiley Online Library
A good correlation was observed between enhanced lung cancer risk and restriction
fragment length polymorphisms (RFLPs) of the P450IA1 gene with the restriction enzyme …

Preventive effects of drinking green tea on cancer and cardiovascular disease: epidemiological evidence for multiple targeting prevention

K Nakachi, S Matsuyama, S Miyake, M Suganuma… - Biofactors, 2000 - Wiley Online Library
The significance of drinking green tea in prevention of two of the main lifestyle‐related
diseases, cancer and cardiovascular disease, was demonstrated in terms of a prospective …

Genetic Linkage of Lung Cancer-Associated MspI Polymorphisms with Amino Acid Replacement in the Heme Binding Region of the Human Cytochrome P450IA1 …

S Hayashi, J Watanabe, K Nakachi… - The Journal of …, 1991 - academic.oup.com
Individuals with high genetic risk of lung cancer had previously been identified by Msp I
polymorphisms of the cytochrome P460IA1 gene. In the present study we analyzed the …