Morphologic and biochemical hallmarks of apoptosis

A Saraste, K Pulkki - Cardiovascular research, 2000 - academic.oup.com
Apoptosis is characterised by a series of typical morphological features, such as shrinkage
of the cell, fragmentation into membrane-bound apoptotic bodies and rapid phagocytosis by …

Fasting is not routinely required for determination of a lipid profile: clinical and laboratory implications including flagging at desirable concentration cut-points—a joint …

BG Nordestgaard, A Langsted, S Mora… - European heart …, 2016 - academic.oup.com
Aims To critically evaluate the clinical implications of the use of non-fasting rather than
fasting lipid profiles and to provide guidance for the laboratory reporting of abnormal non …

Cytokines and cardiomyocyte death

KJ Pulkki - Annals of medicine, 1997 - Taylor & Francis
Cytokines have been associated with the pathogenesis of acute coronary syndromes and
chronic heart failure (CHF), which are both associated with cardiomyocyte loss. In CHF …

Apoptosis in human acute myocardial infarction

A Saraste, K Pulkki, M Kallajoki, K Henriksen… - Circulation, 1997 - Am Heart Assoc
Background After reopening of the infarct-related coronary artery, cardiomyocytes continue
to die during reperfusion. The mechanisms of cell death have been subject to debate. We …

Acute doxorubicin cardiotoxicity involves cardiomyocyte apoptosis

OJ Arola, A Saraste, K Pulkki, M Kallajoki, M Parvinen… - Cancer research, 2000 - AACR
Despite well-documented cardiotoxic effects, doxorubicin remains a major anticancer agent.
To study the role of myocardial apoptosis following doxorubicin administration, male Wistar …

[HTML][HTML] Effects of n-6 PUFAs compared with SFAs on liver fat, lipoproteins, and inflammation in abdominal obesity: a randomized controlled trial

H Bjermo, D Iggman, J Kullberg, I Dahlman… - The American journal of …, 2012 - Elsevier
Background: Replacing SFAs with vegetable PUFAs has cardiometabolic benefits, but the
effects on liver fat are unknown. Increased dietary n-6 PUFAs have, however, also been …

Cardiomyocyte apoptosis and ventricular remodeling after myocardial infarction in rats

E Palojoki, A Saraste, A Eriksson… - American Journal …, 2001 - journals.physiology.org
We investigated the role of cardiomyocyte apoptosis in the remodeling of the left ventricle
from 24 h to 12 wk after myocardial infarction in the rat. Infarct size planimetry, quantification …

Circulating pregnancy-associated plasma protein a predicts outcome in patients with acute coronary syndrome but no troponin I elevation

J Lund, QP Qin, T Ilva, K Pettersson, LM Voipio-Pulkki… - Circulation, 2003 - Am Heart Assoc
Background—Risk stratification in troponin (cTn)-negative acute coronary syndrome (ACS)
remains a clinical challenge. We investigated the predictive value of circulating pregnancy …

Prognostic value of cystatin C in acute heart failure in relation to other markers of renal function and NT-proBNP

J Lassus, VP Harjola, R Sund… - European Heart …, 2007 - academic.oup.com
Aims Cystatin C, a novel marker of renal function, has been implicated as a prognostic
marker in cardiovascular disease. We investigated the prognostic value of cystatin C in …

Effects of an isocaloric healthy N ordic diet on insulin sensitivity, lipid profile and inflammation markers in metabolic syndrome–a randomized study (SYSDIET)

M Uusitupa, K Hermansen… - Journal of internal …, 2013 - Wiley Online Library
Background Different healthy food patterns may modify cardiometabolic risk. We
investigated the effects of an isocaloric healthy N ordic diet on insulin sensitivity, lipid profile …