Genome-wide association study identifies multiple susceptibility loci for pulmonary fibrosis
TE Fingerlin, E Murphy, W Zhang, AL Peljto… - Nature …, 2013 - nature.com
We performed a genome-wide association study of non-Hispanic, white individuals with
fibrotic idiopathic interstitial pneumonias (IIPs; n= 1,616) and controls (n= 4,683), with follow …
fibrotic idiopathic interstitial pneumonias (IIPs; n= 1,616) and controls (n= 4,683), with follow …
Association between the MUC5B promoter polymorphism and survival in patients with idiopathic pulmonary fibrosis
AL Peljto, Y Zhang, TE Fingerlin, SF Ma, JGN Garcia… - Jama, 2013 - jamanetwork.com
Importance Current prediction models of mortality in idiopathic pulmonary fibrosis (IPF),
which are based on clinical and physiological parameters, have modest value in predicting …
which are based on clinical and physiological parameters, have modest value in predicting …
Inhibition and role of let-7d in idiopathic pulmonary fibrosis
KV Pandit, D Corcoran, H Yousef… - American journal of …, 2010 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and usually lethal
fibrotic lung disease characterized by profound changes in epithelial cell phenotype and …
fibrotic lung disease characterized by profound changes in epithelial cell phenotype and …
Peripheral blood proteins predict mortality in idiopathic pulmonary fibrosis
TJ Richards, N Kaminski, F Baribaud… - American journal of …, 2012 - atsjournals.org
Rationale: Idiopathic pulmonary fibrosis (IPF) is a lethal lung disease of unknown etiology
with a variable and unpredictable course. Objectives: The aim of this study was to identify …
with a variable and unpredictable course. Objectives: The aim of this study was to identify …
Gene expression profiles of acute exacerbations of idiopathic pulmonary fibrosis
K Konishi, KF Gibson, KO Lindell… - American journal of …, 2009 - atsjournals.org
Rationale: The molecular mechanisms underlying acute exacerbations of idiopathic
pulmonary fibrosis (IPF) are poorly understood. We studied the global gene expression …
pulmonary fibrosis (IPF) are poorly understood. We studied the global gene expression …
Peripheral blood mononuclear cell gene expression profiles predict poor outcome in idiopathic pulmonary fibrosis
JD Herazo-Maya, I Noth, SR Duncan, SH Kim… - Science translational …, 2013 - science.org
We aimed to identify peripheral blood mononuclear cell (PBMC) gene expression profiles
predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) by performing microarray …
predictive of poor outcomes in idiopathic pulmonary fibrosis (IPF) by performing microarray …
Efficacy of simtuzumab versus placebo in patients with idiopathic pulmonary fibrosis: a randomised, double-blind, controlled, phase 2 trial
G Raghu, KK Brown, HR Collard, V Cottin… - The Lancet …, 2017 - thelancet.com
Background Lysyl oxidase-like 2 (LOXL2) catalyses collagen cross-linking and is implicated
in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to …
in the pathogenesis of idiopathic pulmonary fibrosis (IPF). The aim of this study was to …
WNT5A is a regulator of fibroblast proliferation and resistance to apoptosis
LJ Vuga, A Ben-Yehudah… - American journal of …, 2009 - atsjournals.org
Usual interstitial pneumonia (UIP) is a specific histopathologic pattern of interstitial lung
fibrosis that may be idiopathic or secondary to autoimmune diseases and environmental …
fibrosis that may be idiopathic or secondary to autoimmune diseases and environmental …
Patients with idiopathic pulmonary fibrosis with antibodies to heat shock protein 70 have poor prognoses
RA Kahloon, J Xue, A Bhargava… - American journal of …, 2013 - atsjournals.org
Rationale: Diverse autoantibodies are present in most patients with idiopathic pulmonary
fibrosis (IPF). We hypothesized that specific autoantibodies may associate with IPF …
fibrosis (IPF). We hypothesized that specific autoantibodies may associate with IPF …
CXC motif chemokine 13 (CXCL13) is a prognostic biomarker of idiopathic pulmonary fibrosis
Rationale: CXC motif chemokine 13 (CXCL13) mediates B-cell trafficking and is increased,
proportionately to disease activity, in many antibody-mediated syndromes. Dysregulated B …
proportionately to disease activity, in many antibody-mediated syndromes. Dysregulated B …