User profiles for "author:Koichi Sugimoto"
Koichi SugimotoUniversity of Tsukuba Verified email at u.tsukuba.ac.jp Cited by 1701 |
Modulation of microRNA processing by p53
HI Suzuki, K Yamagata, K Sugimoto, T Iwamoto, S Kato… - Nature, 2009 - nature.com
MicroRNAs (miRNAs) have emerged as key post-transcriptional regulators of gene
expression, involved in diverse physiological and pathological processes. Although miRNAs …
expression, involved in diverse physiological and pathological processes. Although miRNAs …
[HTML][HTML] Reactive carbonyl species: a missing link in ROS signaling
As reactive oxygen species (ROS) play critical roles in plants to determine cell fate in various
physiological situations, there is keen interest in the biochemical processes of ROS signal …
physiological situations, there is keen interest in the biochemical processes of ROS signal …
Selective apoptosis of natural killer‐cell tumours by l‐asparaginase
M Ando, K Sugimoto, T Kitoh, M Sasaki… - British journal of …, 2005 - Wiley Online Library
We examined the effectiveness of various anti‐tumour agents to natural killer (NK)‐cell
tumour cell lines and samples, which are generally resistant to chemotherapy, using flow …
tumour cell lines and samples, which are generally resistant to chemotherapy, using flow …
Autophagy is activated by TGF-β and potentiates TGF-β–mediated growth inhibition in human hepatocellular carcinoma cells
K Kiyono, HI Suzuki, H Matsuyama, Y Morishita… - Cancer research, 2009 - AACR
Transforming growth factor-β (TGF-β) is a multifunctional cytokine that regulates cell growth,
differentiation, and apoptosis of various types of cells. Autophagy is emerging as a critical …
differentiation, and apoptosis of various types of cells. Autophagy is emerging as a critical …
[PDF][PDF] MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation
HI Suzuki, M Arase, H Matsuyama, YL Choi, T Ueno… - Molecular cell, 2011 - cell.com
MicroRNAs (miRNAs) are versatile regulators of gene expression and undergo complex
maturation processes. However, the mechanism (s) stabilizing or reducing these small …
maturation processes. However, the mechanism (s) stabilizing or reducing these small …
Frequent mutations in the p53 gene in human myeloid leukemia cell lines
K Sugimoto, H Toyoshima, R Sakai, K Miyagawa… - 1992 - ashpublications.org
The p53 gene is currently considered to function as a tumor-suppressor gene in various
human malignancies. In hematologic malignancies, alterations in the p53 gene have been …
human malignancies. In hematologic malignancies, alterations in the p53 gene have been …
Intake and transformation to a glycoside of (Z)-3-hexenol from infested neighbors reveals a mode of plant odor reception and defense
K Sugimoto, K Matsui, Y Iijima… - Proceedings of the …, 2014 - National Acad Sciences
Plants receive volatile compounds emitted by neighboring plants that are infested by
herbivores, and consequently the receiver plants begin to defend against forthcoming …
herbivores, and consequently the receiver plants begin to defend against forthcoming …
miR-135b mediates NPM-ALK–driven oncogenicity and renders IL-17–producing immunophenotype to anaplastic large cell lymphoma
H Matsuyama, HI Suzuki, H Nishimori… - Blood, The Journal …, 2011 - ashpublications.org
Many transformed lymphoma cells show immune-phenotypes resembling the corresponding
normal lymphocytes; thus, they provide a guide for proper diagnosis and present promising …
normal lymphocytes; thus, they provide a guide for proper diagnosis and present promising …
Regulation of growth–defense balance by the JASMONATE ZIM‐DOMAIN (JAZ)‐MYC transcriptional module
The plant hormone jasmonate (JA) promotes the degradation of JASMONATE ZIM‐DOMAIN
(JAZ) proteins to relieve repression on diverse transcription factors (TFs) that execute JA …
(JAZ) proteins to relieve repression on diverse transcription factors (TFs) that execute JA …
JAZ repressors of metabolic defense promote growth and reproductive fitness in Arabidopsis
Plant immune responses mediated by the hormone jasmonoyl-l-isoleucine (JA-Ile) are
metabolically costly and often linked to reduced growth. Although it is known that JA-Ile …
metabolically costly and often linked to reduced growth. Although it is known that JA-Ile …