The skeleton's architecture is matched to the changing loads to which it is subjected
because mechanical loading directly or indirectly influences the activity of cell populations to …

If γ-carboxylation, by the vitamin K-cycle, of glutamate residues of bone-matrix peptides is
essential for the formation of bone, the circulating levels of this vitamin might indicate the …

TSH concentration was measured in plasma before and after TRH administration (200 μg,
iv) in 89 patients with documented hypothyroidism consequent to various hypothalamic …

Myocardial preservation by continuous coronary perfusion is compared with cold
cardioplegia. The I L. of St. Thomas' cardioplegic protective solution used for infusion into …

Vitamin K 1 functions in the conversion of glutamate residues, present in certain bone
peptides, into the putatively active γ-carboxyglutamate form. We have shown previously that …

Adult primary myxoedema is usually due to an autoimmune thryoiditis characterized by
progressive shrinking of the thyroid gland, loss of epithelium, dense infiltration by sensitized …

To investigate the possibility that goitrous enlargement in autoimmune thyroid disease could
be induced by autoantibodies stimulating thyroid-cell growth, organ cultures of guineapig …

For as long as cells have been studied by normal light microscopy cytologists have known
that many cells contain small refractile granules, about 0* 5-1, u in diameter. In living …

It was conceivable that the previously reported elevated pentose-shunt activity in human
rheumatoid synoviocytes could be at the expense of glycolytic activity. To test this possibility …

Vitamin K 1 is the intermediate carrier of reducing equivalents in mineralization. In fracture-
healing in the rat metatarsal the primary source of these reducing equivalents appears to be …