Polymerase chain reaction for screening clinical isolates of corynebacteria for the production of diphtheria toxin.

MJ Pallen, AJ Hay, LH Puckey… - Journal of clinical …, 1994 - jcp.bmj.com
AIMS--To assess the performance of the polymerase chain reaction (PCR) when used to
screen rapidly large numbers of corynebacteria for toxin production; and to determine the …

[HTML][HTML] Characterization of multiple enhancer regions upstream of the apolipoprotein (a) gene

DP Wade, LH Puckey, BL Knight, F Acquati… - Journal of Biological …, 1997 - ASBMB
Plasma concentrations of the atherogenic lipoprotein (a)(Lp (a)) are predominantly
determined by inherited sequences within or closely linked to the apolipoprotein (a) gene …

Combinatorial domain hunting: an effective approach for the identification of soluble protein domains adaptable to high‐throughput applications

S Reich, LH Puckey, CL Cheetham, R Harris… - Protein …, 2006 - Wiley Online Library
Exploitation of potential new targets for drug and vaccine development has an absolute
requirement for multimilligram quantities of soluble protein. While recombinant expression of …

Polymorphisms in the apolipoprotein (a) gene and their relationship to allele size and plasma lipoprotein (a) concentration

LH Puckey, RM Lawn, BL Knight - Human molecular genetics, 1997 - academic.oup.com
Genotypes at five previously described polymorphic sites at the apolipoprotein (a) gene
locus have been determined for the members of 27 families as well as for unrelated white …

Sequence and functional changes in a putative enhancer region upstream of the apolipoprotein (a) gene

LH Puckey, BL Knight - Atherosclerosis, 2003 - Elsevier
Two enhancer regions upstream of the apolipoprotein (a)(apo (a)) gene were amplified and
sequenced from subjects who were known to express abnormally high or low amounts of …

Interaction of oestrogen and peroxisome proliferator-activated receptors with apolipoprotein (a) gene enhancers

LH Puckey, BL Knight - Biochemical Journal, 2002 - portlandpress.com
A high plasma concentration of lipoprotein (a)[Lp (a)] confers an increased risk for the
development of coronary heart disease. Hormones, such as oestrogen, are some of the few …

[PDF][PDF] A rapid, simple method for detecting PCR failure

MJ Pallen, LH Puckey, BW Wren - PCR Methods Appl, 1992 - pdfs.semanticscholar.org
The polymerase chain reaction (PCR) holds great potential for the rapid and sensitive
detection of pathogenic microorganisms.(1~ There has been much interest in detecting and …

Variation at position 162 of peroxisome proliferator-activated receptor α does not influence the effect of fibrates on cholesterol or triacylglycerol concentrations in …

LH Puckey, BL Knight - Pharmacogenetics and Genomics, 2001 - journals.lww.com
The fibrate group of drugs are widely used to lower plasma lipid concentrations, especially
in diabetic subjects. They exert their effects by activating peroxisome proliferator-activated …

[CITATION][C] Characterization of multiple enhancer regions upstream of the apolipoprotein (a) gene

DP Wade, LH Puckey, BL Knight, F Acquati… - Journal of Biological …, 1998 - ASBMB
Characterization of multiple enhancer regions upstream of the apolipoprotein(a) gene. Page 1
Additions and Corrections Vol. 272 (1997) 30387–30399 Characterization of multiple enhancer …

[CITATION][C] The genetic regulation of lipoprotein (a) concentration

LH Puckey - 2002 - Imperial College London (University …