User profiles for "author:L New"

Leslie New

Asst. Prof. of Statistics, Ursinus College
Verified email at ursinus.edu
Cited by 1922

Understanding the population consequences of disturbance

E Pirotta, CG Booth, DP Costa… - Ecology and …, 2018 - Wiley Online Library
Managing the nonlethal effects of disturbance on wildlife populations has been a long‐term
goal for decision makers, managers, and ecologists, and assessment of these effects is …

The p38 MAP kinase pathway and its biological function

L New, J Han - Trends in cardiovascular medicine, 1998 - Elsevier
p38 is a mitogen-activated protein (MAP) kinase with structural and functional characteristics
that distinguish it from JNK and ERK MAP kinases. p38 activity is upregulated when cells are …

[HTML][HTML] Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38δ

Y Jiang, H Gram, M Zhao, L New, J Gu, L Feng… - Journal of Biological …, 1997 - ASBMB
We have cloned and characterized a new member of the p38 group of mitogen-activated
protein kinases here termed p38δ. Sequence comparisons revealed that p38δ is …

Insecticide‐treated bednets reduce mortality and severe morbidity from malaria among children on the Kenyan coast

…, VO Mung'Ala, W Muterni, L New… - Tropical Medicine & …, 1996 - Wiley Online Library
New tools to prevent malaria morbidity and mortality are needed to improve child survival in
sub‐Saharan Africa. Insecticide treated bednets (ITBN) have been shown, in one setting …

[HTML][HTML] Receptor tyrosine kinase signaling and targeting in glioblastoma multiforme

M Tilak, J Holborn, LA New, J Lalonde… - International Journal of …, 2021 - mdpi.com
Glioblastoma multiforme (GBM) is amongst the deadliest of human cancers, with a median
survival rate of just over one year following diagnosis. Characterized by rapid proliferation …

MAPKK-independent activation of p38α mediated by TAB1-dependent autophosphorylation of p38α

B Ge, H Gram, F Di Padova, B Huang, L New… - Science, 2002 - science.org
Phosphorylation of mitogen-activated protein kinases (MAPKs) on specific tyrosine and
threonine sites by MAP kinase kinases (MAPKKs) is thought to be the sole activation …

[HTML][HTML] PRAK, a novel protein kinase regulated by the p38 MAP kinase

L New, Y Jiang, M Zhao, K Liu, W Zhu, LJ Flood… - The EMBO …, 1998 - embopress.org
We have identified and cloned a novel serine/threonine kinase, p38-regulated/activated
protein kinase (PRAK). PRAK is a 471 amino acid protein with 20–30% sequence identity to …

Regulation of the MEF2 family of transcription factors by p38

M Zhao, L New, VV Kravchenko, Y Kato… - … and cellular biology, 1999 - Taylor & Francis
Members of the MEF2 family of transcription factors bind as homo-and heterodimers to the
MEF2 site found in the promoter regions of numerous muscle-specific, growth-or stress …

[PDF][PDF] Hypersusceptibility to vesicular stomatitis virus infection in Dicer1-deficient mice is due to impaired miR24 and miR93 expression

M Otsuka, Q Jing, P Georgel, L New, J Chen, J Mols… - Immunity, 2007 - cell.com
Dicer is essential for plant, Caenorhabditis elegans, and Drosophila antiviral responses
because of its role in generating small interfering RNA (siRNA) from viral genomes. We …

[HTML][HTML] PRAK is essential for ras-induced senescence and tumor suppression

P Sun, N Yoshizuka, L New, BA Moser, Y Li, R Liao… - Cell, 2007 - cell.com
Like apoptosis, oncogene-induced senescence is a barrier to tumor development. However,
relatively little is known about the signaling pathways mediating the senescence response …