Background.—Under the auspices of the College of American Pathologists, the current state
of knowledge regarding pathologic prognostic factors (factors linked to outcome) and …

Abstract BACKGROUND The American Joint Committee on Cancer (AJCC), which regularly
reviews TNM staging systems, established a working party to develop recommendations for …

Background The effectiveness of surgery for colorectal cancer depends on it being carried
out safely, which allows most patients to return to productive lives, with an improved …

The purpose of tumour staging for colorectal cancer (CRC) is to help define clinical
management, facilitate communication between physicians, provide a basis for stratification …

Clinically evident anastomotic dehiscence was studied in 1466 patients who had undergone
resection of a large-bowel adenocarcinoma. The overall incidence of anastomotic leakage …

Abstract The Large Bowel Cancer Project is a collaborative prospective study of 4228
patients with a histologically proven adenocarcinoma, of whom 2336 (55 per cent) survived …

Of 4583 patients in the Large Bowel Cancer Project, 713 (16 per cent) were obstructed. The
site of greatest risk was the splenic flexure (49 per cent). Advanced stage was neither the full …

A review of histopathology reports on 2046 patients in the large bowel cancer project
showed considerable observer variation in histological grading. Dukes staging, and lymph …

Abstract 1988 patients with an adenocarcinoma of the rectum (1292; 65 per cent) or
rectosigmoid (696; 35 per cent) have been studied. A resection (1700 patients) or …

Abstract BACKGROUND The American Joint Committee on Cancer®(AJCC) published the
1st edition of the Cancer Staging Manual in 1977 and began using T (tumor extent), N …