Cancer stem cells in colorectal cancer: a review
MJ Munro, SK Wickremesekera, L Peng… - Journal of clinical …, 2018 - jcp.bmj.com
Colorectal cancer (CRC) is the second most common cancer in women and the third most
common in men. Adenocarcinoma accounts for 90% of CRC cases. There has been …
common in men. Adenocarcinoma accounts for 90% of CRC cases. There has been …
[HTML][HTML] Cancer stem cell hierarchy in glioblastoma multiforme
A Bradshaw, A Wickremsekera, ST Tan, L Peng… - Frontiers in …, 2016 - frontiersin.org
Glioblastoma multiforme (GBM), an aggressive tumor that typically exhibits treatment failure
with high mortality rates, is associated with the presence of cancer stem cells (CSCs) within …
with high mortality rates, is associated with the presence of cancer stem cells (CSCs) within …
Role of DGAT enzymes in triacylglycerol metabolism
B Bhatt-Wessel, TW Jordan, JH Miller, L Peng - Archives of biochemistry …, 2018 - Elsevier
The esterification of a fatty acyl moiety to diacylglycerol to form triacylglycerol (TAG) is
catalysed by two diacylglycerol O-acyltransferases (DGATs) encoded by genes belonging to …
catalysed by two diacylglycerol O-acyltransferases (DGATs) encoded by genes belonging to …
Coral holobiont cues prime Endozoicomonas for a symbiotic lifestyle
Endozoicomonas are prevalent, abundant bacterial associates of marine animals, including
corals. Their role in holobiont health and functioning, however, remains poorly understood …
corals. Their role in holobiont health and functioning, however, remains poorly understood …
Central metabolic responses to the overproduction of fatty acids in Escherichia coli based on 13C‐metabolic flux analysis
We engineered a fatty acid overproducing Escherichia coli strain through overexpressing
tesA (“pull”) and fadR (“push”) and knocking out fadE (“block”). This “pull‐push‐block” …
tesA (“pull”) and fadR (“push”) and knocking out fadE (“block”). This “pull‐push‐block” …
A Gaussian process-based dynamic surrogate model for complex engineering structural reliability analysis
G Su, L Peng, L Hu - Structural Safety, 2017 - Elsevier
The performance function of a complex engineering structure is always highly nonlinear and
implicit, and its reliability needs to be evaluated through a time-consuming computer codes …
implicit, and its reliability needs to be evaluated through a time-consuming computer codes …
Symbiosis induces widespread changes in the proteome of the model cnidarian Aiptasia
CA Oakley, MF Ameismeier, L Peng… - Cellular …, 2016 - Wiley Online Library
Coral reef ecosystems are metabolically founded on the mutualism between corals and
photosynthetic dinoflagellates of the genus Symbiodinium. The glass anemone Aiptasia sp …
photosynthetic dinoflagellates of the genus Symbiodinium. The glass anemone Aiptasia sp …
Production of structured phospholipids by lipase-catalyzed acidolysis: optimization using response surface methodology
L Peng, X Xu, H Mu, CE Høy, J Adler-Nissen - Enzyme and microbial …, 2002 - Elsevier
Structured phospholipids were produced by lipase-catalyzed acidolysis between soybean
phospholipids and free fatty acids. For this purpose three commercially available …
phospholipids and free fatty acids. For this purpose three commercially available …
Thermal Shock Induces Host Proteostasis Disruption and Endoplasmic Reticulum Stress in the Model Symbiotic Cnidarian Aiptasia
CA Oakley, E Durand, SP Wilkinson… - Journal of Proteome …, 2017 - ACS Publications
Coral bleaching has devastating effects on coral survival and reef ecosystem function, but
many of the fundamental cellular effects of thermal stress on cnidarian physiology are …
many of the fundamental cellular effects of thermal stress on cnidarian physiology are …
Metabolic flux analysis for a ppc mutant Escherichia coli based on 13C-labelling experiments together with enzyme activity assays and intracellular metabolite …
L Peng, MJ Arauzo-Bravo… - FEMS microbiology …, 2004 - academic.oup.com
The physiology and central metabolism of a ppc mutant Escherichia coli were investigated
based on the metabolic flux distribution obtained by 13C-labelling experiments using gas …
based on the metabolic flux distribution obtained by 13C-labelling experiments using gas …