User profiles for "author:M Odenthal"

Margarete Odenthal

Pathology, University of Cologne
Verified email at uni-koeln.de
Cited by 10059

[HTML][HTML] Exosomes as miRNA carriers: formation–function–future

X Yu, M Odenthal, JWU Fries - International journal of molecular sciences, 2016 - mdpi.com
Exosomes, which are one of the smallest extracellular vesicles released from cells, have
been shown to carry different nucleic acids, including microRNAs (miRNAs). miRNAs …

[HTML][HTML] microRNA are central players in anti-and profibrotic gene regulation during liver fibrosis

…, N Elfimova, J Huang, M Odenthal - Frontiers in …, 2012 - frontiersin.org
MicroRNA (miRNA) are small non-coding RNA molecules that posttranscriptionally effect
mRNA stability and translation by targeting the 3′-untranslated region (3′-UTR) of various …

[HTML][HTML] Circulating tumor DNA as an emerging liquid biopsy biomarker for early diagnosis and therapeutic monitoring in hepatocellular carcinoma

…, Q Dong, N Ren, M Liu, M Odenthal… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
As one of the most common malignant tumors worldwide, hepatocellular carcinoma (HCC) is
known for its poor prognosis due to diagnosis only in advanced stages. Nearly 50% of the …

[HTML][HTML] Single-cell profiling of tumor heterogeneity and the microenvironment in advanced non-small cell lung cancer

…, X Li, L Hou, C Wu, C Su, S Ren, M Odenthal… - Nature …, 2021 - nature.com
Lung cancer is a highly heterogeneous disease. Cancer cells and cells within the tumor
microenvironment together determine disease progression, as well as response to or …

Labelfree fully electronic nucleic acid detection system based on a field-effect transistor device

…, D Mayer, S Böcker-Meffert, M Odenthal… - Biosensors and …, 2004 - Elsevier
The labelfree detection of nucleic acid sequences is one of the modern attempts to develop
quick, cheap and miniaturised hand-held devices for the future genetic testing in …

[PDF][PDF] MicroRNA gene expression profile of hepatitis C virus–associated hepatocellular carcinoma

…, P Schirmacher, HP Dienes, M Odenthal - …, 2008 - Wiley Online Library
MicroRNAs are small noncoding RNAs that regulate gene expression by targeting
messenger RNAs (mRNAs) through translational repression or RNA degradation. Many …

[HTML][HTML] Hox-C9 activates the intrinsic pathway of apoptosis and is associated with spontaneous regression in neuroblastoma

…, H Deubzer, V Ehemann, B Brors, M Odenthal… - Cell death & …, 2013 - nature.com
Neuroblastoma is an embryonal malignancy of the sympathetic nervous system.
Spontaneous regression and differentiation of neuroblastoma is observed in a subset of …

Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells

J Trebicka, M Hennenberg, M Odenthal, K Shir… - Journal of …, 2010 - Elsevier
BACKGROUND & AIMS: Activation of hepatic stellate cells (HSC) and transdifferentiation to
myofibroblasts following liver injury is the main culprit for hepatic fibrosis. Myofibroblasts …

Intrahepatic myeloid-cell aggregates enable local proliferation of CD8+ T cells and successful immunotherapy against chronic viral liver infection

…, Z Abdullah, FA Schildberg, M Odenthal… - Nature …, 2013 - nature.com
Chronic infection is difficult to overcome because of exhaustion or depletion of cytotoxic
effector CD8+ T cells (cytotoxic T lymphoytes (CTLs)). Here we report that signaling via Toll …

[HTML][HTML] Identification of serum angiopoietin-2 as a biomarker for clinical outcome of colorectal cancer patients treated with bevacizumab-containing therapy

…, B Cremer, H Kashkar, M Odenthal… - British journal of …, 2010 - nature.com
Background: The combination of chemotherapy with the vascular endothelial growth factor
(VEGF) antibody bevacizumab is a standard of care in advanced colorectal cancer (CRC) …