Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG
S Shibutani, M Takeshita, AP Grollman - Nature, 1991 - nature.com
OXIDATIVE damage to DNA, reflected in the formation of 8-oxo-7-hydrodeoxyguanosine (8-
oxodG) 1, 2, may be important in mutagenesis, carcinogenesis and the ageing process3, 4 …
oxodG) 1, 2, may be important in mutagenesis, carcinogenesis and the ageing process3, 4 …
Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome
K Tamura, M Kaneda, M Futagawa, M Takeshita… - International journal of …, 2019 - Springer
Lynch syndrome is a cancer-predisposing syndrome inherited in an autosomal-dominant
manner, wherein colon cancer and endometrial cancer develop frequently in the family, it …
manner, wherein colon cancer and endometrial cancer develop frequently in the family, it …
Current treatment strategies and factors influencing outcome in patients with bacterial brain abscess
M Takeshita, M Kagawa, M Izawa, K Takakura - Acta neurochirurgica, 1998 - Springer
We clearly determined the key to managing patients with brain abscess by retrospectively
evaluating the factors affecting poor outcome in these patients. This study included 113 …
evaluating the factors affecting poor outcome in these patients. This study included 113 …
[HTML][HTML] Role of neuroinflammation and blood-brain barrier permutability on migraine
…, S Suzuki, N Morishita, M Takeshita… - International journal of …, 2021 - mdpi.com
Currently, migraine is treated mainly by targeting calcitonin gene-related peptides, although
the efficacy of this method is limited and new treatment strategies are desired …
the efficacy of this method is limited and new treatment strategies are desired …
Anaplastic large cell lymphomas expressing the novel chimeric protein p80NPM/ALK: a distinct clinicopathologic entity
…, R Ichinohasama, M Abe, T Akagi, M Takeshita… - 1995 - ashpublications.org
Anaplastic large cell lymphoma (ALCL) is a subtype of non-Hodgkin's lymphoma
characterized by the CD30+ large neoplastic cells and sometimes carries at (2; 5)(p23; q35) …
characterized by the CD30+ large neoplastic cells and sometimes carries at (2; 5)(p23; q35) …
[HTML][HTML] Oligodeoxynucleotides containing synthetic abasic sites. Model substrates for DNA polymerases and apurinic/apyrimidinic endonucleases.
M Takeshita, CN Chang, F Johnson, S Will… - Journal of Biological …, 1987 - Elsevier
A synthetic procedure has been developed by which stable abasic sites are introduced into
oligodeoxynucleotides at any desired position in the sequence. A modified tetrahydrofuran …
oligodeoxynucleotides at any desired position in the sequence. A modified tetrahydrofuran …
Site-specific mutagenesis using a gapped duplex vector: a study of translesion synthesis past 8-oxodeoxyguanosine in E. coli
…, C Ou, V Bodepudi, F Johnson, M Takeshita… - Mutation Research/DNA …, 1991 - Elsevier
We have constructed a gapped plasmid vector in which a single defined lesion is
introduced, site-specifically, within a single-strand region. Efficiency of translesional …
introduced, site-specifically, within a single-strand region. Efficiency of translesional …
Predictive value of endoscopic ultrasonography for regression of gastric low grade and high grade MALT lymphomas after eradication ofHelicobacter pylori
S Nakamura, T Matsumoto, H Suekane, M Takeshita… - Gut, 2001 - gut.bmj.com
BACKGROUND While a close association between gastric mucosa associated lymphoid
tissue (MALT) lymphoma and Helicobacter pylori infection has been established, there are …
tissue (MALT) lymphoma and Helicobacter pylori infection has been established, there are …
[HTML][HTML] Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA (∗)
DM Wilson, M Takeshita, AP Grollman… - Journal of Biological …, 1995 - ASBMB
The major apurinic/apyrimidinic (AP) endonuclease of human cells, the Ape protein, incises
DNA adjacent to abasic sites to initiate DNA repair and counteract the cytotoxic and …
DNA adjacent to abasic sites to initiate DNA repair and counteract the cytotoxic and …
Environmental DNA enables detection of terrestrial mammals from forest pond water
Terrestrial animals must have frequent contact with water to survive, implying that
environmental DNA (eDNA) originating from those animals should be detectable from …
environmental DNA (eDNA) originating from those animals should be detectable from …