Helicobacter pylori: perspectives and time trends
The discovery of Helicobacter pylori three decades ago is a modern medical success story. It
markedly changed our understanding of the pathophysiology of gastroduodenal diseases …
markedly changed our understanding of the pathophysiology of gastroduodenal diseases …
Gastric cancer: clinical aspects, epidemiology and molecular background
J Bornschein, T Rokkas, M Selgrad… - Helicobacter, 2011 - Wiley Online Library
The validity and usefulness of the 7th edition of the UICC tumor node metastasis
classification in the context of clinical management of gastric cancer are discussed. The …
classification in the context of clinical management of gastric cancer are discussed. The …
Treatment of Helicobacter pylori
M Selgrad, P Malfertheiner - Current Opinion in Gastroenterology, 2011 - journals.lww.com
Treatment of H. pylori infection is challenged by a dramatic fall in eradication rates all over
the world. Newer regimens have been introduced including sequential, quadruple therapies …
the world. Newer regimens have been introduced including sequential, quadruple therapies …
Chemopreventive properties of pinoresinol-rich olive oil involve a selective activation of the ATM–p53 cascade in colon cancer cell lines
L Fini, E Hotchkiss, V Fogliano, G Graziani… - …, 2008 - academic.oup.com
The Mediterranean diet is rich in extra virgin olive oil (EVOO) and associated with a lower
incidence of colorectal cancer. EVOO contains phenolic extracts with potential …
incidence of colorectal cancer. EVOO contains phenolic extracts with potential …
H. pylori Infection Is a Key Risk Factor for Proximal Gastric Cancer
J Bornschein, M Selgrad, M Warnecke… - Digestive diseases and …, 2010 - Springer
Background Despite evidence for the association of distal gastric cancer (GC) with the H.
pylori infection, relevance of the infection for proximal GC is uncertain. Aims We analysed …
pylori infection, relevance of the infection for proximal GC is uncertain. Aims We analysed …
[HTML][HTML] Different antibiotic susceptibility between antrum and corpus of the stomach, a possible reason for treatment failure of Helicobacter pylori infection
M Selgrad, I Tammer, C Langner… - World journal of …, 2014 - ncbi.nlm.nih.gov
AIM: To assess whether antibiotic resistance varies between the antrum and corpus of the
stomach of patients that are either Helicobacter pylori (H. pylori) therapy-naive or pre …
stomach of patients that are either Helicobacter pylori (H. pylori) therapy-naive or pre …
[HTML][HTML] Serological assessment of gastric mucosal atrophy in gastric cancer
J Bornschein, M Selgrad, T Wex, D Kuester… - BMC …, 2012 - Springer
Background Non-invasive tools for gastric cancer screening and diagnosis are lacking.
Serological testing with the detection of pepsinogen 1 (PG1), pepsinogen 2 (PG2) and …
Serological testing with the detection of pepsinogen 1 (PG1), pepsinogen 2 (PG2) and …
[HTML][HTML] Annurca apple polyphenols have potent demethylating activity and can reactivate silenced tumor suppressor genes in colorectal cancer cells
The CpG island methylator phenotype is characterized by DNA hypermethylation in the
promoters of tumor suppressor genes with silencing of transcription. Hypermethylation of the …
promoters of tumor suppressor genes with silencing of transcription. Hypermethylation of the …
Antibiotic susceptibility of Helicobacter pylori in central Germany and its relationship with the number of eradication therapies
M Selgrad, J Meile, J Bornschein… - European Journal of …, 2013 - journals.lww.com
Antibiotic susceptibility of Helicobacter pylori in central... : European Journal of
Gastroenterology & Hepatology Antibiotic susceptibility of Helicobacter pylori in central …
Gastroenterology & Hepatology Antibiotic susceptibility of Helicobacter pylori in central …
Efficacy, immunogenicity, and safety of a parenteral vaccine against Helicobacter pylori in healthy volunteers challenged with a Cag-positive strain: a randomised …
P Malfertheiner, M Selgrad, T Wex, B Romi… - The Lancet …, 2018 - thelancet.com
Background Intramuscular immunisation with a vaccine composed of three recombinant
Helicobacter pylori antigens—vacuolating cytotoxin A (VacA), cytotoxin-associated antigen …
Helicobacter pylori antigens—vacuolating cytotoxin A (VacA), cytotoxin-associated antigen …