User profiles for "author:Michael Toss"

MICHAEL TOSS

Assistant Lecturer, Department of Pathology, South Egypt Cancer Institute, Assiut University
Verified email at aun.edu.eg
Cited by 2067

Current and future applications of artificial intelligence in pathology: a clinical perspective

EA Rakha, M Toss, S Shiino, P Gamble… - Journal of clinical …, 2021 - jcp.bmj.com
During the last decade, a dramatic rise in the development and application of artificial
intelligence (AI) tools for use in pathology services has occurred. This trend is often …

Assessment of mitotic activity in breast cancer: revisited in the digital pathology era

A Ibrahim, A Lashen, M Toss, R Mihai… - Journal of Clinical …, 2022 - jcp.bmj.com
The assessment of cell proliferation is a key morphological feature for diagnosing various
pathological lesions and predicting their clinical behaviour. Visual assessment of mitotic …

Centrosome amplification: a quantifiable cancer cell trait with prognostic value in solid malignancies

K Mittal, J Kaur, M Jaczko, G Wei, MS Toss… - Cancer and Metastasis …, 2021 - Springer
Numerical and/or structural centrosome amplification (CA) is a hallmark of cancers that is
often associated with the aberrant tumor karyotypes and poor clinical outcomes …

[HTML][HTML] Determining breast cancer biomarker status and associated morphological features using deep learning

P Gamble, R Jaroensri, H Wang, F Tan… - Communications …, 2021 - nature.com
Background Breast cancer management depends on biomarkers including estrogen
receptor, progesterone receptor, and human epidermal growth factor receptor 2 …

[HTML][HTML] SlideGraph+: Whole slide image level graphs to predict HER2 status in breast cancer

W Lu, M Toss, M Dawood, E Rakha, N Rajpoot… - Medical Image …, 2022 - Elsevier
Human epidermal growth factor receptor 2 (HER2) is an important prognostic and predictive
factor which is overexpressed in 15–20% of breast cancer (BCa). The determination of its …

[HTML][HTML] Predictors of pathological complete response to neoadjuvant treatment and changes to post-neoadjuvant HER2 status in HER2-positive invasive breast …

A Katayama, IM Miligy, S Shiino, MS Toss, K Eldib… - Modern Pathology, 2021 - Elsevier
The response of human epidermal growth factor receptor2 (HER2)-positive breast cancer
(BC) patients to anti-HER2 targeted therapy is significant. However, the response is not …

Heterogeneity of tumour‐infiltrating lymphocytes in breast cancer and its prognostic significance

M Althobiti, MA Aleskandarany, C Joseph… - …, 2018 - Wiley Online Library
Background and aims Tumour‐infiltrating lymphocytes (TIL s) in breast cancer (BC) provide
prognostic and predictive information. The aim of this study was to assess the spatial and …

[HTML][HTML] Prognostic significance of tumor-infiltrating lymphocytes in ductal carcinoma in situ of the breast

MS Toss, I Miligy, A Al-Kawaz, M Alsleem, H Khout… - Modern Pathology, 2018 - Elsevier
Tumor-infiltrating lymphocytes (TILs) provide prognostic value in invasive breast cancer and
guidelines for their assessment have been published. This study aims to evaluate:(a) …

Semantic annotation for computational pathology: multidisciplinary experience and best practice recommendations

N Wahab, IM Miligy, K Dodd, H Sahota… - The Journal of …, 2022 - Wiley Online Library
Recent advances in whole‐slide imaging (WSI) technology have led to the development of a
myriad of computer vision and artificial intelligence‐based diagnostic, prognostic, and …

Overexpression of the cancer stem cell marker CD133 confers a poor prognosis in invasive breast cancer

C Joseph, M Arshad, S Kurozomi, M Althobiti… - Breast Cancer Research …, 2019 - Springer
Purpose CD133/prominin 1 is a cancer stem cell marker associated with cancer progression
and patient outcome in a variety of solid tumours, but its role in invasive breast cancer (BC) …