User profiles for "author:Michele Schirru"

Michele Schirru

AC2T
Verified email at ac2t.at
Cited by 220

Safety and antitumor activity of the multitargeted pan-TRK, ROS1, and ALK inhibitor entrectinib: combined results from two phase I trials (ALKA-372-001 and …

A Drilon, S Siena, SHI Ou, M Patel, MJ Ahn, J Lee… - Cancer discovery, 2017 - AACR
Entrectinib, a potent oral inhibitor of the tyrosine kinases TRKA/B/C, ROS1, and ALK, was
evaluated in two phase I studies in patients with advanced or metastatic solid tumors …

Predictive value of VEGF gene polymorphisms for metastatic colorectal cancer patients receiving first-line treatment including fluorouracil, irinotecan, and …

V Formica, R Palmirotta, G Del Monte… - International journal of …, 2011 - Springer
Purpose The aim of this study is to evaluate the influence of germline vascular endothelial
growth factor (VEGF) gene polymorphisms (VGPs) on the efficacy of the anti-VEGF antibody …

[HTML][HTML] Robot localization in water pipes using acoustic signals and pose graph optimization

R Worley, K Ma, G Sailor, MM Schirru, R Dwyer-Joyce… - Sensors, 2020 - mdpi.com
One of the most fundamental tasks for robots inspecting water distribution pipes is
localization, which allows for autonomous navigation, for faults to be communicated, and for …

New EHL modeling data for the reference liquids squalane and squalane plus polyisoprene

SS Bair, O Andersson, FS Qureshi… - Tribology …, 2018 - Taylor & Francis
An important part of the new quantitative approach to elastohydrodynamic lubrication (EHL)
is the use of reference liquids with well-characterized thermophysical properties. New …

Robot mapping and localisation in metal water pipes using hydrophone induced vibration and map alignment by dynamic time warping

K Ma, MM Schirru, AH Zahraee… - … on Robotics and …, 2017 - ieeexplore.ieee.org
Water is a highly valuable resource so asset management of associated infrastructure is of
critical importance. Water distribution pipe networks are usually buried, and so are difficult to …

PipeSLAM: Simultaneous localisation and mapping in feature sparse water pipes using the Rao-Blackwellised particle filter

K Ma, M Schirru, AH Zahraee… - 2017 IEEE …, 2017 - ieeexplore.ieee.org
Water, a valuable resource, is usually distributed through urban environments by buried
pipes. These pipes are difficult to access for inspection, maintenance and repair. This makes …

TRKA expression and NTRK1 gene copy number across solid tumours

G Mauri, E Valtorta, G Cerea, A Amatu… - Journal of Clinical …, 2018 - jcp.bmj.com
Aims Neurotrophic Tropomyosin Kinase Receptor 1 (NTRK1) gene encodes for the protein
Tropomyosin-related kinase A (TRKA). Deregulated activity of TRKA has been shown to …

[BOOK][B] Development of an ultrasonic sensing technique to measure lubricant viscosity in engine journal bearing in-situ

M Schirru - 2017 - books.google.com
This thesis presents a novel ultrasonic instrument for non-invasive and in-situ
characterization of journal bearing lubricant viscosity. In particular, the application to journal …

A model for the reflection of shear ultrasonic waves at a thin liquid film and its application to viscometry in a journal bearing

MM Schirru, RS Dwyer-Joyce - Proceedings of the Institution …, 2016 - journals.sagepub.com
The apparent viscosity of oils in the thin layers that exist in machine elements such as gears
and bearings is very different to that in the bulk. In addition, oils in lubricating layers are …

[HTML][HTML] Pooled analysis of clinical outcome of patients with chemorefractory metastatic colorectal cancer treated within phase I/II clinical studies based on individual …

A Sartore-Bianchi, A Amatu, E Bonazzina, S Stabile… - Targeted Oncology, 2017 - Springer
Background Patients with metastatic colorectal cancer (mCRC) refractory to standard
therapies have a poor prognosis. In this setting, recruitment into clinical trials is warranted …