[PDF][PDF] Promotion of hepatocellular carcinoma by the intestinal microbiota and TLR4

DH Dapito, A Mencin, GY Gwak, JP Pradere, MK Jang… - Cancer cell, 2012 - cell.com
Increased translocation of intestinal bacteria is a hallmark of chronic liver disease and
contributes to hepatic inflammation and fibrosis. Here we tested the hypothesis that the …

[HTML][HTML] Role of microbiota-derived metabolites in alcoholic and non-alcoholic fatty liver diseases

JW Park, SE Kim, NY Lee, JH Kim, JH Jung… - International Journal of …, 2021 - mdpi.com
Chronic liver disease encompasses diseases that have various causes, such as alcoholic
liver disease (ALD) and non-alcoholic fatty liver disease (NAFLD). Gut microbiota …

[PDF][PDF] Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice

JP Pradere, J Kluwe, S De Minicis, JJ Jiao… - …, 2013 - Wiley Online Library
Although it is well established that hepatic macrophages play a crucial role in the
development of liver fibrosis, the underlying mechanisms remain largely elusive. Moreover …

[HTML][HTML] Primary biliary cholangitis and primary sclerosing cholangitis: current knowledge of pathogenesis and therapeutics

JW Park, JH Kim, SE Kim, JH Jung, MK Jang, SH Park… - Biomedicines, 2022 - mdpi.com
Cholangiopathies encompass various biliary diseases affecting the biliary epithelium,
resulting in cholestasis, inflammation, fibrosis, and ultimately liver cirrhosis. Primary biliary …

A prospective nationwide study of drug-induced liver injury in Korea

KT Suk, DJ Kim, CH Kim, SH Park… - Official journal of the …, 2012 - journals.lww.com
OBJECTIVES: To address a growing concern about drug-induced liver injury (DILI), a
nationwide study was performed to investigate the significance of DILI in Korea. METHODS …

Clinical aspects of tumor necrosis factor-α signaling in hepatocellular carcinoma

MK Jang, H Su Kim, YH Chung - Current pharmaceutical …, 2014 - ingentaconnect.com
Tumor necrosis factor alpha (TNF-α) is a multi-functional cytokine that regulates a variety of
signaling pathways implicated in inflammation, immunity, cell death (apoptosis), cell survival …

[HTML][HTML] Diagnostic value of PIVKA-II and alpha-fetoprotein in hepatitis B virus-associated hepatocellular carcinoma

SI Seo, HS Kim, WJ Kim, WG Shin, DJ Kim… - World journal of …, 2015 - ncbi.nlm.nih.gov
AIM: To determine the cutoff values and to compare the diagnostic role of alpha-fetoprotein
(AFP) and prothrombin induced by vitamin K absence-II (PIVKA-II) in chronic hepatitis B …

Clinical predictors for delirium tremens in alcohol dependence

JH Lee, MK Jang, JY Lee, SM Kim… - Journal of …, 2005 - Wiley Online Library
Abstract Background and Aims: This study was aimed to find clinical predictors for
developing delirium tremens (DT) in alcohol dependence. Methods: This cohort study was …

[PDF][PDF] MicroRNA‐21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis

JM Caviglia, J Yan, MK Jang, GY Gwak, S Affo… - …, 2018 - Wiley Online Library
Fibrosis and cancer represent two major complications of chronic liver disease. MicroRNAs
have been implicated in the development of fibrosis and cancer, thus constituting potential …

Association of polymorphism of IL-10 and TNF-A genes with gastric cancer in Korea

JY Lee, HY Kim, KH Kim, SM Kim, MK Jang, JY Park… - Cancer letters, 2005 - Elsevier
We performed this study to determine the role of polymorphisms of the IL-10 and TNF-α
promoter genes in the carcinogenesis/pathogenesis of gastric cancer (GC) and peptic ulcer …