Fast field-cycling magnetic resonance imaging

DJ Lurie, S Aime, S Baroni, NA Booth… - Comptes Rendus …, 2010 - Elsevier
Magnetic resonance imaging (MRI) and fast field-cycling (FFC) NMR are both well-
developed methods. The combination of these techniques, namely fast field-cycling …

Fibrinolysis and thrombosis

NA Booth - Best Practice & Research Clinical Haematology, 1999 - Elsevier
The fibrinolytic system generates plasmin, which dissolves fibrin in haemostatic plugs and in
thrombi. It is often regarded simply as a secondary phenomenon responsive to the …

Plasminogen activator inhibitor (PAI‐1) in plasma and platelets

NA Booth, AJ Simpson, A Croll… - British journal of …, 1988 - Wiley Online Library
The distribution of PAI‐1 in the plasma and platelets of normal individuals and of patients
with platelet abnormalities was studied. An ELISA, capable of measuring PAI‐1 in plasma at …

Monocyte plasminogen activator inhibitor 2 (PAI-2) inhibits u-PA-mediated fibrin clot lysis and is cross-linked to fibrin

H Ritchie, LA Robbie, S Kinghorn… - Thrombosis and …, 1999 - thieme-connect.com
Plasminogen activator inhibitor 2 (PAI-2) is a major product of activated human monocytes.
Here we show that monocytes inhibited u-PA-but not t-PA-mediated fibrinolysis, by secreting …

Candida albicans binds human plasminogen: identification of eight plasminogen‐binding proteins

JD Crowe, IK Sievwright, GC Auld… - Molecular …, 2003 - Wiley Online Library
Several microbial pathogens augment their invasive potential by binding and activating
human plasminogen to generate the proteolytic enzyme plasmin. Yeast cells and cell wall …

Distribution of plasminogen activator inhibitor (PAI-1) in tissues.

AJ Simpson, NA Booth, NR Moore… - Journal of clinical …, 1991 - jcp.bmj.com
Extracts of human tissue were analysed for plasminogen activator inhibitor (PAI-1) antigen
and activity. PAI-1 was localised in tissues by an immunochemical method, using …

The antifibrinolytic function of factor XIII is exclusively expressed through α2-antiplasmin cross-linking

SR Fraser, NA Booth, NJ Mutch - Blood, The Journal of the …, 2011 - ashpublications.org
Factor XIII (FXIII) generates fibrin-fibrin and fibrin-inhibitor cross-links. Our flow model, which
is sensitive to cross-linking, was used to assess the effects of FXIII and the fibrinolytic …

Functional factor XIII-A is exposed on the stimulated platelet surface

JL Mitchell, AS Lionikiene, SR Fraser… - Blood, The Journal …, 2014 - ashpublications.org
Factor XIII (FXIII) stabilizes thrombi against fibrinolysis by cross-linking α2-antiplasmin
(α2AP) to fibrin. Cellular FXIII (FXIII-A) is abundant in platelets, but the extracellular functions …

From famine to feast: the role of methylglyoxal production in Escherichia coli

S Tötemeyer, NA Booth, WW Nichols… - Molecular …, 1998 - Wiley Online Library
The enzyme methylglyoxal synthase (MGS) was partially purified from Escherichia coli
extracts, and the amino‐terminal sequence of candidate proteins was determined, based on …

[HTML][HTML] TAFIa, PAI‐1 and α2‐antiplasmin: complementary roles in regulating lysis of thrombi and plasma clots

NJ Mutch, L Thomas, NR Moore, KM Lisiak… - Journal of Thrombosis …, 2007 - Elsevier
Summary PAI‐1 and α 2‐antiplasmin (α 2 AP) are the principal direct inhibitors of fibrinolytic
proteases. Thrombin activatable fibrinolysis inhibitor (TAFI), a plasma procarboxypeptidase …