Direct antimicrobial resistance prediction from clinical MALDI-TOF mass spectra using machine learning
Early use of effective antimicrobial treatments is critical for the outcome of infections and the
prevention of treatment resistance. Antimicrobial resistance testing enables the selection of …
prevention of treatment resistance. Antimicrobial resistance testing enables the selection of …
Effect of mutation and genetic background on drug resistance in Mycobacterium tuberculosis
…, K Jaton, GE Pfyffer, S Borrell, O Dubuis… - Antimicrobial agents …, 2012 - Am Soc Microbiol
Bacterial factors may contribute to the global emergence and spread of drug-resistant
tuberculosis (TB). Only a few studies have reported on the interactions between different …
tuberculosis (TB). Only a few studies have reported on the interactions between different …
[HTML][HTML] Air-conditioner cooling towers as complex reservoirs and continuous source of Legionella pneumophila infection evidenced by a genomic analysis study in …
…, S Gautsch, R Spieler-Denz, O Dubuis… - …, 2019 - eurosurveillance.org
Introduction Water supply and air-conditioner cooling towers (ACCT) are potential sources of
Legionella pneumophila infection in people. During outbreaks, traditional typing methods …
Legionella pneumophila infection in people. During outbreaks, traditional typing methods …
[HTML][HTML] “Pseudo-Beijing”: Evidence for Convergent Evolution in the Direct Repeat Region of Mycobacterium tuberculosis
L Fenner, B Malla, B Ninet, O Dubuis, D Stucki… - PloS one, 2011 - journals.plos.org
Background Mycobacterium tuberculosis has a global population structure consisting of six
main phylogenetic lineages associated with specific geographic regions and human …
main phylogenetic lineages associated with specific geographic regions and human …
Clinical outcome in pneumococcal meningitis correlates with CSF lipoteichoic acid concentrations
O Schneider, U Michel, G Zysk, O Dubuis, R Nau - Neurology, 1999 - AAN Enterprises
Article abstract Lipoteichoic and teichoic acids are components of the cell wall of
Streptococcus pneumoniae. A recently developed enzyme immunoassay was used in …
Streptococcus pneumoniae. A recently developed enzyme immunoassay was used in …
[HTML][HTML] Colistin resistance in Gram-negative bacteria analysed by five phenotypic assays and inference of the underlying genomic mechanisms
…, HMB Seth-Smith, N Joosse, C Lang, O Dubuis… - BMC microbiology, 2021 - Springer
Background Colistin is used against multi-drug resistant pathogens, yet resistance emerges
through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes …
through dissemination of plasmid-mediated genes (mcr) or chromosomal mutation of genes …
[HTML][HTML] Accuracy of Sensititre YeastOne echinocandins epidemiological cut-off values for identification of FKS mutant Candida albicans and Candida glabrata: a ten …
…, R Frei, R Hertel, M Dolina, O Petrini, O Dubuis… - Clinical microbiology …, 2018 - Elsevier
Objectives Echinocandins represent the first-line treatment of candidaemia. Acquired
echinocandin resistance is mainly observed among Candida albicans and Candida glabrata …
echinocandin resistance is mainly observed among Candida albicans and Candida glabrata …
[HTML][HTML] Characterising the epidemic spread of influenza A/H3N2 within a city through phylogenetics
…, M Syedbasha, D Lang, RA Neher, O Dubuis… - PLoS …, 2020 - journals.plos.org
Infecting large portions of the global population, seasonal influenza is a major burden on
societies around the globe. While the global source sink dynamics of the different seasonal …
societies around the globe. While the global source sink dynamics of the different seasonal …
Determinants of SARS-CoV-2 transmission to guide vaccination strategy in an urban area
…, M Siegemund, H Pargger, D Ciardo, O Dubuis… - Virus …, 2022 - academic.oup.com
Transmission chains within small urban areas (accommodating∼ 30 per cent of the
European population) greatly contribute to case burden and economic impact during the …
European population) greatly contribute to case burden and economic impact during the …
A critical assessment of the prognostic value of HIV-1 RNA levels and CD4+ cell counts in HIV-infected patients
…, TV Perneger, B Hirschel, O Dubuis… - Archives of internal …, 1998 - jamanetwork.com
Objective To determine to what extent human immunodeficiency type 1 (HIV-1) RNA levels
and CD4+ cell counts predict clinical outcomes in a general HIV-1–infected population …
and CD4+ cell counts predict clinical outcomes in a general HIV-1–infected population …