The bacterium Helicobacter pylori is found in c. 40% of the population and is responsible for
the development of duodenal disease. Triple treatment with a proton-pump inhibitor or …

Matrix metalloproteinases (MMPs) and their inhibitors are important in connective tissue re-
modelling in diseases of the cardiovascular system, such as atherosclerosis. Various …

Infection with Helicobacter pylori (H. pylori), especially CagA+ strains, has been associated
with an increased risk of noncardia gastric adenocarcinoma. The relationship with junctional …

OBJECTIVE--To examine the relation between the use of aspirin and non-steroidal anti-
inflammatory drugs and the presence of asymptomatic colorectal adenomas. DESIGN--Case …

The urease of Helicobacter pylori (formerly Campylobacter pylori) has been partly purified
by fast protein liquid chromatography. This material contained 10 nm doughnut-like …

The ADAMTS (a disintegrin-like and metalloproteinase domain with thrombospondin type I
motifs) family of proteases plays a role in pathological conditions including arthritis, cancer …

We describe the discovery of novel inhibitors of prostaglandin D2 synthase (PGDS) through
fragment-based lead generation and structure-based drug design. A library of 2500 low …

The effects on self management of asthma of a specially prepared book and audiocassette
tape with similar contents were observed in a controlled study of 177 patients with asthma in …

Campylobacter pyloridis was isolated from 77% of 220 (35%) unselected adults undergoing
gastroscopy. Isolation was significantly associated with histological gastritis (p less than …

We sought to explain seasonality and other aspects of Campylobacter jejuni epidemiology
by integrating population genetic and epidemiological analysis in a large 3-year …