Leptospirosis: a zoonotic disease of global importance

AR Bharti, JE Nally, JN Ricaldi, MA Matthias… - The Lancet infectious …, 2003 - thelancet.com
In the past decade, leptospirosis has emerged as a globally important infectious disease. It
occurs in urban environments of industrialised and developing countries, as well as in rural …

Leptospirosis in humans

DA Haake, PN Levett - Leptospira and leptospirosis, 2015 - Springer
Leptospirosis is a widespread and potentially fatal zoonosis that is endemic in many tropical
regions and causes large epidemics after heavy rainfall and flooding. Infection results from …

Leptospirosis: a forgotten zoonosis?

PN Levett - Clinical and Applied Immunology Reviews, 2004 - Elsevier
Leptospirosis is a common zoonosis, which is often overlooked in the differential diagnosis
of febrile illness. The epidemiology of leptospirosis has undergone major changes, with a …

The leptospiral major outer membrane protein LipL32 is a lipoprotein expressed during mammalian infection

DA Haake, G Chao, RL Zuerner, JK Barnett… - Infection and …, 2000 - Am Soc Microbiol
We report the cloning of the gene encoding the 32-kDa lipoprotein, designated LipL32, the
most prominent protein in the leptospiral protein profile. We obtained the N-terminal amino …

Usefulness of serologic analysis as a predictor of the infecting serovar in patients with severe leptospirosis

PN Levett - Clinical Infectious Diseases, 2003 - academic.oup.com
The diagnosis of leptospirosis is often made using the microscopic agglutination test (MAT),
in which live antigens representing> 20 serogroups undergo reaction with patient serum …

Detection of pathogenic leptospires by real-time quantitative PCR

PN Levett, RE Morey, RL Galloway… - Journal of Medical …, 2005 - microbiologyresearch.org
Definitive diagnosis of leptospirosis has traditionally depended upon the isolation of
leptospires from clinical specimens or the demonstration of seroconversion in paired acute …

[PDF][PDF] Assessment of the efficacy of an IgM-elisa and microscopic agglutination test (MAT) in the diagnosis of acute leptospirosis.

P Cumberland, CO Everard… - The American journal of …, 1999 - researchgate.net
In a prospective study in Barbados between 1979 and 1989, 321 cases were diagnosed in
638 patients presenting at a hospital with symptoms of leptospirosis. Initial diagnosis was …

Evaluation of four commercially available rapid serologic tests for diagnosis of leptospirosis

MD Bajani, DA Ashford, SL Bragg… - Journal of clinical …, 2003 - Am Soc Microbiol
Four rapid tests for the serologic diagnosis of leptospirosis were evaluated, and the
performance of each was compared with that of the current standard, the microscopic …

[HTML][HTML] What Makes a Bacterial Species Pathogenic?:Comparative Genomic Analysis of the Genus Leptospira

DE Fouts, MA Matthias, H Adhikarla… - PLoS neglected …, 2016 - journals.plos.org
Leptospirosis, caused by spirochetes of the genus Leptospira, is a globally widespread,
neglected and emerging zoonotic disease. While whole genome analysis of individual …

Atopic dermatitis is associated with a functional mutation in the promoter of the CC chemokine RANTES

RG Nickel, V Casolaro, U Wahn, K Beyer… - The Journal of …, 2000 - journals.aai.org
Up-regulation of CC chemokine expression characterizes allergic inflammation and atopic
diseases. A functional mutation in the proximal promoter of the RANTES gene has been …