[PDF][PDF] Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors
Blastemal histology in chemotherapy-treated pediatric Wilms tumors (nephroblastoma) is
associated with adverse prognosis. To uncover the underlying tumor biology and find …
associated with adverse prognosis. To uncover the underlying tumor biology and find …
[HTML][HTML] Cancer testis antigen expression in testicular germ cell tumorigenesis
PK Bode, A Thielken, S Brandt, A Barghorn, B Lohe… - Modern …, 2014 - nature.com
Cancer testis antigens are encoded by germ line-associated genes that are present in
normal germ cells of testis and ovary but not in differentiated tissues. Their expression in …
normal germ cells of testis and ovary but not in differentiated tissues. Their expression in …
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance
SG Danielli, E Porpiglia, AJ De Micheli, N Navarro… - Science …, 2023 - science.org
Rhabdomyosarcoma (RMS) is a group of pediatric cancers with features of developing
skeletal muscle. The cellular hierarchy and mechanisms leading to developmental arrest …
skeletal muscle. The cellular hierarchy and mechanisms leading to developmental arrest …
[HTML][HTML] A versatile modular vector system for rapid combinatorial mammalian genetics
J Albers, C Danzer, M Rechsteiner… - The Journal of …, 2015 - Am Soc Clin Investig
Here, we describe the multiple lentiviral expression (MuLE) system that allows multiple
genetic alterations to be introduced simultaneously into mammalian cells. We created a …
genetic alterations to be introduced simultaneously into mammalian cells. We created a …
[HTML][HTML] Tracing clonal dynamics reveals that two-and three-dimensional patient-derived cell models capture tumor heterogeneity of clear cell renal cell carcinoma
HA Bolck, C Corrò, A Kahraman, A von Teichman… - European urology …, 2021 - Elsevier
Background Extensive DNA sequencing has led to an unprecedented view of the diversity of
individual genomes and their evolution among patients with clear cell renal cell carcinoma …
individual genomes and their evolution among patients with clear cell renal cell carcinoma …
[HTML][HTML] SalvGlandDx–a comprehensive salivary gland neoplasm specific next generation sequencing panel to facilitate diagnosis and identify therapeutic targets
SN Freiberger, M Brada, C Fritz, S Höller, A Vogetseder… - Neoplasia, 2021 - Elsevier
Diagnosis of salivary gland neoplasms is often challenging due to their high morphological
diversity and overlaps. Several recurrent molecular alterations have been described …
diversity and overlaps. Several recurrent molecular alterations have been described …
[HTML][HTML] Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies
DO Azorsa, PK Bode, M Wachtel, ATC Cheuk… - Modern Pathology, 2021 - Elsevier
Alveolar Rhabdomyosarcoma (ARMS) is an aggressive pediatric cancer with about 80% of
cases characterized by either at (1; 13)(p36; q14) or t (2; 13)(q35; q14), which results in the …
cases characterized by either at (1; 13)(p36; q14) or t (2; 13)(q35; q14), which results in the …
[HTML][HTML] MAGEC2 is a sensitive and novel marker for seminoma: a tissue microarray analysis of 325 testicular germ cell tumors
PK Bode, A Barghorn, FR Fritzsche, MO Riener… - Modern Pathology, 2011 - Elsevier
Melanoma-associated gene C2 (MAGEC2) is a recently identified cancer testis antigen
expressed in normal testicular and placental tissue. It has been detected in some human …
expressed in normal testicular and placental tissue. It has been detected in some human …
[HTML][HTML] Structural and perfusion magnetic resonance imaging of congenital lung malformations
CJ Kellenberger, C Amaxopoulou, U Moehrlen… - Pediatric …, 2020 - Springer
Background A radiation-free advanced imaging modality is desirable for investigating
congenital thoracic malformations in young children. Objective To describe magnetic …
congenital thoracic malformations in young children. Objective To describe magnetic …
Glycogen storage disease type VI: clinical course and molecular background
TRJ Aeppli, D Rymen, G Allegri, PK Bode… - European journal of …, 2020 - Springer
Glycogen storage disease type VI (GSD-VI; also known as Hers disease, liver
phosphorylase deficiency) is caused by mutations in the gene coding for glycogen …
phosphorylase deficiency) is caused by mutations in the gene coding for glycogen …