Blastemal histology in chemotherapy-treated pediatric Wilms tumors (nephroblastoma) is
associated with adverse prognosis. To uncover the underlying tumor biology and find …

Cancer testis antigens are encoded by germ line-associated genes that are present in
normal germ cells of testis and ovary but not in differentiated tissues. Their expression in …

Rhabdomyosarcoma (RMS) is a group of pediatric cancers with features of developing
skeletal muscle. The cellular hierarchy and mechanisms leading to developmental arrest …

Here, we describe the multiple lentiviral expression (MuLE) system that allows multiple
genetic alterations to be introduced simultaneously into mammalian cells. We created a …

Background Extensive DNA sequencing has led to an unprecedented view of the diversity of
individual genomes and their evolution among patients with clear cell renal cell carcinoma …

Diagnosis of salivary gland neoplasms is often challenging due to their high morphological
diversity and overlaps. Several recurrent molecular alterations have been described …

Alveolar Rhabdomyosarcoma (ARMS) is an aggressive pediatric cancer with about 80% of
cases characterized by either at (1; 13)(p36; q14) or t (2; 13)(q35; q14), which results in the …

Melanoma-associated gene C2 (MAGEC2) is a recently identified cancer testis antigen
expressed in normal testicular and placental tissue. It has been detected in some human …

Background A radiation-free advanced imaging modality is desirable for investigating
congenital thoracic malformations in young children. Objective To describe magnetic …

Glycogen storage disease type VI (GSD-VI; also known as Hers disease, liver
phosphorylase deficiency) is caused by mutations in the gene coding for glycogen …