User profiles for "author:Phedias Diamandis"

Phedias Diamandis

Associate Professor, University of Toronto
Verified email at mail.utoronto.ca
Cited by 2476

Three-dimensional modeling of human neurodegeneration: brain organoids coming of age

K Grenier, J Kao, P Diamandis - Molecular psychiatry, 2020 - nature.com
The prevalence of dementia and other neurodegenerative diseases is rapidly increasing in
aging nations. These relentless and progressive diseases remain largely without disease …

World Health Organization 2016 Classification of Central Nervous System Tumors.

P Diamandis, K Aldape - Neurologic clinics, 2018 - europepmc.org
The recent update of the World Health Organization (WHO) classification of tumors of the
central nervous system represents a paradigm shift. Previous iterations of the classification …

Unsupervised machine learning in pathology: the next frontier

A Roohi, K Faust, U Djuric… - Surgical Pathology …, 2020 - surgpath.theclinics.com
Applications of artificial intelligence and particularly deep learning to aid pathologists in
carrying out laborious and qualitative tasks in histopathologic image analysis have now …

[HTML][HTML] Fine-tuning and training of densenet for histopathology image representation using tcga diagnostic slides

A Riasatian, M Babaie, D Maleki, S Kalra… - Medical image …, 2021 - Elsevier
Feature vectors provided by pre-trained deep artificial neural networks have become a
dominant source for image representation in recent literature. Their contribution to the …

[HTML][HTML] Physician perspectives on integration of artificial intelligence into diagnostic pathology

S Sarwar, A Dent, K Faust, M Richer, U Djuric… - NPJ digital …, 2019 - nature.com
Advancements in computer vision and artificial intelligence (AI) carry the potential to make
significant contributions to health care, particularly in diagnostic specialties such as …

[HTML][HTML] Absence of chronic traumatic encephalopathy in retired football players with multiple concussions and neurological symptomatology

LN Hazrati, MC Tartaglia, P Diamandis… - Frontiers in human …, 2013 - frontiersin.org
Background: Chronic traumatic encephalopathy (CTE) is the term coined for the
neurodegenerative disease often suspected in athletes with histories of repeated …

[HTML][HTML] Precision histology: how deep learning is poised to revitalize histomorphology for personalized cancer care

U Djuric, G Zadeh, K Aldape, P Diamandis - NPJ precision oncology, 2017 - nature.com
Accurate interpretation of the hematoxylin and eosin (H&E) slide has remained the
foundation of pathological analysis and diagnostic medicine for over a century. 1 For the …

[HTML][HTML] Topographic mapping of the glioblastoma proteome reveals a triple-axis model of intra-tumoral heterogeneity

KHB Lam, AJ Leon, W Hui, SCE Lee, I Batruch… - Nature …, 2022 - nature.com
Glioblastoma is an aggressive form of brain cancer with well-established patterns of intra-
tumoral heterogeneity implicated in treatment resistance and progression. While regional …

Chemical genetics reveals a complex functional ground state of neural stem cells

P Diamandis, J Wildenhain, ID Clarke… - Nature chemical …, 2007 - nature.com
The identification of self-renewing and multipotent neural stem cells (NSCs) in the
mammalian brain holds promise for the treatment of neurological diseases and has yielded …

[HTML][HTML] Pan-cancer diagnostic consensus through searching archival histopathology images using artificial intelligence

S Kalra, HR Tizhoosh, S Shah, C Choi… - NPJ digital …, 2020 - nature.com
The emergence of digital pathology has opened new horizons for histopathology. Artificial
intelligence (AI) algorithms are able to operate on digitized slides to assist pathologists with …