Cyclosporin A in patients receiving renal allografts from cadaver donors

RY Calne, S Thiru, P McMaster, GN Craddock… - The Lancet, 1978 - Elsevier
Seven patients on dialysis with renal failure received transplants from mismatched cadaver
donors and were treated with cyclosporin A (CyA), initially as the sole immunosuppressive …

Cyclosporin A initially as the only immunosuppressant in 34 recipients of cadaveric organs: 32 kidneys, 2 pancreases, and 2 livers

RY Calne, K Rolles, S Thiru, P McMaster, GN Craddock… - The Lancet, 1979 - Elsevier
Abstract 34 patients treated with cyclosporin A received 36 cadaveric organ allografts (32
kidneys, 2 pancreases, and 2 livers). 26 kidneys are still supporting life, 3 after more than a …

A surgical experience with five hundred thirty liver transplants in the rat

N Kamada, RY Calne - Surgery, 1983 - surgjournal.com
A surgical experience with 530 orthotopic liver transplants in rats is reviewed with technical
details. Liver transplantation in the rat can provide important data in a variety of areas …

Induction of immunological tolerance by porcine liver allografts

RY Calne, RA Sells, JR Pena, DR Davis, PR Millard… - Nature, 1969 - nature.com
Liver allografting experiments with pigs show that animals given no immunosuppression will
survive for prolonged periods with orthotopic liver transplants. Similar animals can reject …

Liver transplantation for malignant disease. Results in 93 consecutive patients.

JG O'Grady, RJ Polson, K Rolles, RY Calne… - Annals of …, 1988 - ncbi.nlm.nih.gov
Ninety-three patients with malignant disease underwent orthotopic liver transplantation
between May 1968 and April 1987 in the Cambridge/King's College Hospital program. Of 50 …

Liver transplantation in man—I, observations on technique and organization in five cases

RY Calne, R Williams - Br Med J, 1968 - bmj.com
In view of the extreme sensitivity of the human liver to ischaemic damage, the organization of
clinical transplantation is of necessity complicated. From our preliminary experience of five …

Normalised intrinsic mortality risk in liver transplantation: European Liver Transplant Registry study

R Adam, V Cailliez, P Majno, V Karam, P McMaster… - The Lancet, 2000 - thelancet.com
Background No model exists for liver transplantation to estimate the mortality risk in a given
patient, and no standard by which to assess performance in different centres. We …

Immunological tolerance–the liver effect

RY Calne - Immunological reviews, 2000 - Wiley Online Library
The developing immune system in the embryo is programmed to accept all its own tissues
as self‐products and not react against them. It has been the aim of transplantation research …

Cyclosporine: five years' experience in cadaveric renal transplantation

RM Merion, DJG White, S Thiru… - New England Journal …, 1984 - Mass Medical Soc
Using a retrospective analysis we compared 79 recipients of cadaveric renal allografts who
were treated with cyclosporine as the sole initial immunosuppressant and 29 concurrent …

Recurrence of primary biliary cirrhosis after liver transplantation

J Neuberger, B Portmann… - … England Journal of …, 1982 - Mass Medical Soc
Three patients who had undergone orthotopic liver transplantation for primary biliary
cirrhosis and were being maintained on immunosuppressive therapy were investigated 3 …