[HTML][HTML] Intramolecular Interactions and Regulation of Cofactor Binding by the Four Repressive Elements in the Caspase Recruitment Domain-containing Protein 11 …
RP Jattani, JM Tritapoe, JL Pomerantz - Journal of Biological Chemistry, 2016 - ASBMB
The CARD11 signaling scaffold transmits signaling between antigen receptors on B and T
lymphocytes and the transcription factor NF-κB during the adaptive immune response …
lymphocytes and the transcription factor NF-κB during the adaptive immune response …
[HTML][HTML] Cooperative control of caspase recruitment domain-containing protein 11 (CARD11) signaling by an unusual array of redundant repressive elements*♦
RP Jattani, JM Tritapoe, JL Pomerantz - Journal of Biological Chemistry, 2016 - ASBMB
Several classes of signaling proteins contain autoinhibitory domains that prevent
unwarranted signaling and coordinate the induction of activity in response to external cues …
unwarranted signaling and coordinate the induction of activity in response to external cues …
Negative regulation of CARD11 signaling and lymphoma cell survival by the E3 ubiquitin ligase RNF181
SM Pedersen, W Chan, RP Jattani… - … and cellular biology, 2016 - Taylor & Francis
NF-κB activation downstream of antigen receptor engagement is a highly regulated event
required for lymphocyte activation during the adaptive immune response. The pathway is …
required for lymphocyte activation during the adaptive immune response. The pathway is …
[HTML][HTML] Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling
Z Wang, SM Hutcherson, C Yang, RP Jattani… - Journal of Biological …, 2019 - ASBMB
The activation of key signaling pathways downstream of antigen receptor engagement is
critically required for normal lymphocyte activation during the adaptive immune response …
critically required for normal lymphocyte activation during the adaptive immune response …
Detection of genome-wide copy number variants in myeloid malignancies using next-generation sequencing
W Shen, CN Paxton, P Szankasi, M Longhurst… - Journal of Clinical …, 2018 - jcp.bmj.com
Aims Genetic abnormalities, including copy number variants (CNV), copy number neutral
loss of heterozygosity (CN-LOH) and gene mutations, underlie the pathogenesis of myeloid …
loss of heterozygosity (CN-LOH) and gene mutations, underlie the pathogenesis of myeloid …
Correction for Pedersen et al., Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181
SM Pedersen, W Chan, RP Jattani… - Molecular and cellular …, 2016 - ncbi.nlm.nih.gov
AJ, Treumann A, Moran N. 2008. RN181, a novel ubiquitin E3 ligase that interacts with the
KVGFFKR motif of platelet integrin alpha (IIb) beta3. Biochem Biophys Res Commun 369 …
KVGFFKR motif of platelet integrin alpha (IIb) beta3. Biochem Biophys Res Commun 369 …
Functional Elements within CARD11'S Inhibitory Domain Dictate Downstream Signaling to NF-Kappa B in Lymphocytes
RP Jattani - 2015 - search.proquest.com
Antigen (Ag) receptor engagement on lymphocytes triggers a signaling cascade that
phosphorylates the scaffold protein CARD11 in its inhibitory domain (ID) and transforms it …
phosphorylates the scaffold protein CARD11 in its inhibitory domain (ID) and transforms it …