User profiles for "author:Raymond C Chan"

Raymond C Chan

Sentara Healthcare
Verified email at sentara.com
Cited by 236

Recommendations to improve the usability of drug-drug interaction clinical decision support alerts

TH Payne, LE Hines, RC Chan… - Journal of the …, 2015 - academic.oup.com
Objective: To establish preferred strategies for presenting drug-drug interaction (DDI) clinical
decision support alerts. Materials and Methods: A DDI Clinical Decision Support Conference …

Chromosome cohesion is regulated by a clock gene paralogue TIM-1

RC Chan, A Chan, M Jeon, TF Wu, D Pasqualone… - Nature, 2003 - nature.com
Faithful transmission of the genome requires that a protein complex called cohesin
establishes and maintains the regulated linkage between replicated chromosomes before …

Comprehensive volumetric optical microscopy in vivo

SH Yun, GJ Tearney, BJ Vakoc, M Shishkov, WY Oh… - Nature medicine, 2006 - nature.com
Comprehensive volumetric microscopy of epithelial, mucosal and endothelial tissues in
living human patients would have a profound impact in medicine by enabling diagnostic …

Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by “resting state” functional magnetic resonance …

S Lui, T Li, W Deng, L Jiang, Q Wu… - Archives of general …, 2010 - jamanetwork.com
Context Most of what we know about antipsychotic drug effects is at the receptor level, distal
from the neural system effects that mediate their clinical efficacy. Studying cerebral function …

Retinal nerve fiber layer thickness map determined from optical coherence tomography images

M Mujat, RC Chan, B Cense, BH Park, C Joo… - Optics express, 2005 - opg.optica.org
We introduce a method to determine the retinal nerve fiber layer (RNFL) thickness in OCT
images based on anisotropic noise suppression and deformable splines. Spectral-Domain …

The polypyrimidine tract binding protein binds upstream of neural cell-specific c-src exon N1 to repress the splicing of the intron downstream

RC Chan, DL Black - Molecular and cellular biology, 1997 - Am Soc Microbiol
The neural cell-specific N1 exon of the c-src pre-mRNA is both negatively regulated in
nonneural cells and positively regulated in neurons. We previously identified conserved …

Multicenter evaluation of the Accelerate PhenoTest BC kit for rapid identification and phenotypic antimicrobial susceptibility testing using morphokinetic cellular …

P Pancholi, KC Carroll, BW Buchan… - Journal of clinical …, 2018 - Am Soc Microbiol
We describe results from a multicenter study evaluating the Accelerate Pheno system, a first
of its kind diagnostic system that rapidly identifies common bloodstream pathogens from …

The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event.

H Min, RC Chan, DL Black - Genes & development, 1995 - genesdev.cshlp.org
The proteins and RNA regulatory elements that control tissue-specific pre-mRNA splicing in
mammalian cells are mostly unknown. In this study, a set of proteins is identified that binds to …

Tissue Elasticity Estimation with Optical Coherence Elastography: Toward Mechanical Characterization of In Vivo Soft Tissue

AS Khalil, RC Chan, AH Chau, BE Bouma… - Annals of biomedical …, 2005 - Springer
High-resolution imaging provides a significant means for accurate material modulus
estimation and mechanical characterization. Within the realm of in vivo soft tissue …

High-field MRI reveals an acute impact on brain function in survivors of the magnitude 8.0 earthquake in China

S Lui, X Huang, L Chen, H Tang… - Proceedings of the …, 2009 - National Acad Sciences
Besides the enormous medical and economic consequences, national disasters, such as
the Wenchuan 8.0 earthquake, also pose a risk to the mental health of survivors. In this …