The most common cause of lower urinary tract obstruction in male infants is posterior
urethral valves. Although the incidence has remained stable, the neonatal mortality for this …

Mortality in patients with alcoholic hepatitis (AH) remains high, and although corticosteroids
are widely used for treatment, the results vary considerably. In AH, neutrophils are primed …

The pathophysiological basis of acute-on-chronic liver failure (ACLF) is unclear but systemic
inflammatory response is thought to be important. In patients with ACLF, the molecular …

Almost one-quarter of the children referred to a pediatric urologist for obstructive uropathy
suffer from an obstructive megaureter. However, not all megaureters are due to obstruction …

Background/Aims: Severe alcoholic hepatitis (AH) is associated with high mortality. Tumor
necrosis factor-alpha (TNFα) has been demonstrated to play an important role in its …

This study explores the hypothesis that the inflammatory response induced by administration
of lipopolysaccharide (LPS) exacerbates brain edema in cirrhotic rats; and if so whether this …

Purpose: Augmentation cystoplasty using gastrointestinal segments in children/adolescents
with medically refractory neurogenic bladder is associated with significant complications. We …

Hyperammonemia is a feature of liver failure, which is associated with increased risk of
infection. The aims of the present study were to determine in vitro, in rats fed an …

We measured the serum levels of phylloquinone (vitamin K1) and of the menaquinones, MK‐
7 and MK‐8, in a group of 51 women with a mean age of 81 years who were studied within a …

Naphthoquinnone vitamins (vitamins K) are widely recognized for their role in the γ-
carboxylation of specific glutamyl residues in coagulation, anti-coagulation and extra …