User profiles for "author:Soo Yong Tan"
Soo-Yong TanAssociate Professor, National University of Singapore Verified email at nus.edu.sg Cited by 4226 |
Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions
Insufficient awareness of the centrality of pathology and laboratory medicine (PALM) to a
functioning health-care system at policy and governmental level, with the resultant …
functioning health-care system at policy and governmental level, with the resultant …
Pharmacological significance of the non-canonical NF-κB pathway in tumorigenesis
D Morgan, M Garg, V Tergaonkar, SY Tan… - Biochimica et Biophysica …, 2020 - Elsevier
The understanding of the impact of the non-canonical NF-κB (nuclear factor kappa-light-
chain-enhancer of activated B cells) pathway in several human diseases including …
chain-enhancer of activated B cells) pathway in several human diseases including …
Epstein–Barr virus-associated T-and NK-cell lymphoproliferative diseases: an update and diagnostic approach
Summary Epstein–Barr virus (EBV)-positive T-cell and natural killer (NK)-cell
lymphoproliferative diseases (EBV-TNKLPD) are a group of uncommon disorders …
lymphoproliferative diseases (EBV-TNKLPD) are a group of uncommon disorders …
MYC regulates the core pre-mRNA splicing machinery as an essential step in lymphomagenesis
Deregulated expression of the MYC transcription factor occurs in most human cancers and
correlates with high proliferation, reprogrammed cellular metabolism and poor prognosis …
correlates with high proliferation, reprogrammed cellular metabolism and poor prognosis …
Janus kinase 3–activating mutations identified in natural killer/T-cell Lymphoma
The molecular pathogenesis of natural killer/T-cell lymphoma (NKTCL) is not well
understood. We conducted whole-exome sequencing and identified Janus kinase 3 (JAK3) …
understood. We conducted whole-exome sequencing and identified Janus kinase 3 (JAK3) …
Oncogenic activation of the STAT3 pathway drives PD-L1 expression in natural killer/T-cell lymphoma
TL Song, ML Nairismägi, Y Laurensia… - Blood, The Journal …, 2018 - ashpublications.org
Mature T-cell lymphomas, including peripheral T-cell lymphoma (PTCL) and extranodal
NK/T-cell lymphoma (NKTL), represent a heterogeneous group of non-Hodgkin lymphomas …
NK/T-cell lymphoma (NKTL), represent a heterogeneous group of non-Hodgkin lymphomas …
Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers
The ubiquitin-like modifier (UBL) family has recently generated much interest in the scientific
community, as it is implicated to play important regulatory roles via novel protein–protein …
community, as it is implicated to play important regulatory roles via novel protein–protein …
[HTML][HTML] Antisense oligonucleotide–mediated MDM4 exon 6 skipping impairs tumor growth
M Dewaele, T Tabaglio, K Willekens… - The Journal of …, 2016 - Am Soc Clin Investig
MDM4 is a promising target for cancer therapy, as it is undetectable in most normal adult
tissues but often upregulated in cancer cells to dampen p53 tumor-suppressor function. The …
tissues but often upregulated in cancer cells to dampen p53 tumor-suppressor function. The …
Targeting of the MNK–eIF4E axis in blast crisis chronic myeloid leukemia inhibits leukemia stem cell function
S Lim, TY Saw, M Zhang, MR Janes… - Proceedings of the …, 2013 - National Acad Sciences
Chronic myeloid leukemia responds well to therapy targeting the oncogenic fusion protein
BCR-ABL1 in chronic phase, but is resistant to treatment after it progresses to blast crisis …
BCR-ABL1 in chronic phase, but is resistant to treatment after it progresses to blast crisis …
[PDF][PDF] Simultaneous inhibition of PI3Kδ and PI3Kα induces ABC-DLBCL regression by blocking BCR-dependent and-independent activation of NF-κB and AKT
J Paul, M Soujon, AM Wengner, S Zitzmann-Kolbe… - Cancer cell, 2017 - cell.com
Compared with follicular lymphoma, high PI3Kα expression was more prevalent in diffuse
large B cell lymphoma (DLBCL), although both tumor types expressed substantial PI3Kδ …
large B cell lymphoma (DLBCL), although both tumor types expressed substantial PI3Kδ …