Autoimmune hepatitis (AIH), primary biliary cirrhosis, and primary sclerosing cholangitis are
the three major autoimmune diseases affecting the liver, and of these three, AIH is the most …

Histological assessments continue to play an important role in the diagnosis and
management of liver allograft rejection. The changes occurring in acute and chronic …

With improved long-term survival following liver transplantation (LT), issues relating to the
assessment of the liver allograft in long-term survivors are becoming increasingly relevant …

Summary Background Glucagon-like peptide-1 (GLP-1) analogues reduce hepatic steatosis,
concentrations of liver enzymes, and insulin resistance in murine models of fatty liver …

Background & Aims: Histologic examination of a liver biopsy specimen is regarded as the
reference standard for detecting liver fibrosis. Biopsy can be painful and hazardous, and …

LYMPHOCYTE migration from blood into tissue depends on integrin-mediated adhesion to
endothelium1–4. Adhesion requires not only integrin ligands on the endothelium, but also …

The role played by chemokines in regulating the selective recruitment of lymphocytes to
different tissue compartments in disease is poorly characterized. In hepatitis C infection …

There is a limited access to liver transplantation, however, many organs are discarded
based on subjective assessment only. Here we report the VITTAL clinical trial (ClinicalTrials …

Primary sclerosing cholangitis (PSC), a chronic inflammatory liver disease characterized by
progressive bile duct destruction, develops as an extra-intestinal complication of …

Liver biopsy is required when clinically important information about the diagnosis, prognosis
or management of a patient cannot be obtained by safer means, or for research purposes …