Protein kinases as targets for anticancer agents: from inhibitors to useful drugs

…, G Fendrich, J Liebetanz, J Mestan, T O'Reilly… - Pharmacology & …, 2002 - Elsevier
Many components of mitogenic signaling pathways in normal and neoplastic cells have
been identified, including the large family of protein kinases, which function as components …

Tyrosine kinase inhibitors: from rational design to clinical trials

…, P Furet, P Manley, T O'Reilly… - Medicinal research …, 2001 - Wiley Online Library
Protein kinases play a crucial role in signal transduction as well as in cellular proliferation,
differentiation, and various regulatory mechanisms. The inhibition of growth related kinases …

Inhibitors of protein kinases: CGP 41251, a protein kinase inhibitor with potential as an anticancer agent

…, F Hofmann, S Ferrari, H Mett, T O'Reilly… - Pharmacology & …, 1999 - Elsevier
CGP 41251 was originally identified as an inhibitor of protein kinase C (PKC), inhibiting
mainly the conventional PKC subtypes, and subsequently shown to inhibit the vascular …

What is web 2.0

T O'reilly - 2005 - books.google.com
The bursting of the dot-com bubble in the fall of 2001 marked a turning point for the web.
Many people concluded that the web was overhyped, when in fact bubbles and consequent …

[BOOK][B] What is web 2.0

T O'reilly - 2009 - books.google.com
The concept of" Web 2.0" began with a conference brainstorming session between O'Reilly
and MediaLive International. Dale Dougherty, web pioneer and O'Reilly VP, noted that far …

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced …

…, J Frei, F Hofmann, J Mestan, H Mett, T O'Reilly… - Cancer research, 2000 - AACR
Abstract PTK787/ZK 222584 (1-[4-chloroanilino]-4-[4-pyridylmethyl] phthalazine succinate)
is a potent inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinases …

Government as a Platform

T O'Reilly - Innovations: technology, governance, globalization, 2011 - direct.mit.edu
Tim O'Reilly is the founder and CEO of O'Reilly Media, Inc., thought by many to be the best
computer book publisher in the world. In addition to Foo Camps (“Friends of O'Reilly” …

[BOOK][B] Web squared: Web 2.0 five years on

T O'Reilly, J Battelle - 2009 - books.google.com
Ever since we first introduced the term Web 2.0, people have been asking, What™ s next?
Assuming that Web 2.0 was meant to be a kind of software version number (rather than a …

[HTML][HTML] Cloning of a human seven-transmembrane domain receptor, LESTR, that is highly expressed in leukocytes.

M Loetscher, T Geiser, T O'Reilly, R Zwahlen… - Journal of Biological …, 1994 - Elsevier
Several chemotactic agonists including interleukin-8 (IL-8) and related cytokines have been
shown to activate and attract leukocytes via seven-transmembrane domain, GTP-binding …

Web 2.0: compact definition

T O'reilly - 2005 - academia.edu
Web 2.0 is the network as platform, spanning all connected devices; Web 2.0 applications
are those that make the most of the intrinsic advantages of that platform: delivering software …