The EMT-activator ZEB1 promotes tumorigenicity by repressing stemness-inhibiting microRNAs
U Wellner, J Schubert, UC Burk, O Schmalhofer… - Nature cell …, 2009 - nature.com
Invasion and metastasis of carcinomas is promoted by the activation of the
embryonic'epithelial to mesenchymal transition'(EMT) program, which triggers cellular …
embryonic'epithelial to mesenchymal transition'(EMT) program, which triggers cellular …
The lymph node ratio is the strongest prognostic factor after resection of pancreatic cancer
Introduction Survival after surgery of pancreatic cancer is still poor, even after curative
resection. Some prognostic factors like the status of the resection margin, lymph node (LN) …
resection. Some prognostic factors like the status of the resection margin, lymph node (LN) …
Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase
DA Ruess, GJ Heynen, KJ Ciecielski, J Ai… - Nature medicine, 2018 - nature.com
The ubiquitously expressed non-receptor protein tyrosine phosphatase SHP2, encoded by
PTPN11, is involved in signal transduction downstream of multiple growth factor, cytokine …
PTPN11, is involved in signal transduction downstream of multiple growth factor, cytokine …
[HTML][HTML] ESOPEC: prospective randomized controlled multicenter phase III trial comparing perioperative chemotherapy (FLOT protocol) to neoadjuvant …
Background Recent randomized controlled trials comparing neoadjuvant chemoradiation
plus surgery or perioperative chemotherapy plus surgery with surgery alone showed …
plus surgery or perioperative chemotherapy plus surgery with surgery alone showed …
Management of delayed visceral arterial bleeding after pancreatic head resection
F Makowiec, H Riediger, W Euringer, M Uhl… - Journal of …, 2005 - Springer
Despite low mortality, postoperative complications are still relatively frequent after pancreatic
head resection. The occurrence of delayed visceral arterial bleeding from erosions or …
head resection. The occurrence of delayed visceral arterial bleeding from erosions or …
Risk factors for complications after pancreatic head resection
U Adam, F Makowiec, H Riediger, WD Schareck… - The American Journal of …, 2004 - Elsevier
BACKGROUND: Postoperative morbidity is high after pancreatic head resections. Data
about risk factors are controversial. The aim of this study was to evaluate risk factors for …
about risk factors are controversial. The aim of this study was to evaluate risk factors for …
[HTML][HTML] A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperatively
UF Wellner, G Kayser, H Lapshyn, O Sick, F Makowiec… - Hpb, 2010 - Elsevier
Background Postoperative pancreatic fistula (POPF) is regarded as the most serious
complication of pancreatic surgery. The preoperative risk stratification of patients by simple …
complication of pancreatic surgery. The preoperative risk stratification of patients by simple …
Postoperative morbidity and long-term survival after pancreaticoduodenectomy with superior mesenterico-portal vein resection
H Riediger, F Makowiec, E Fischer, U Adam… - Journal of …, 2006 - Springer
The role of superior mesenteric-portal vein resection (SM-PVR) for vein invasion or tumor
adherence during pancreatoduodenectomy (PD) is still under debate. We investigated …
adherence during pancreatoduodenectomy (PD) is still under debate. We investigated …
ZEB 1‐associated drug resistance in cancer cells is reversed by the class I HDAC inhibitor mocetinostat
S Meidhof, S Brabletz, W Lehmann… - EMBO molecular …, 2015 - embopress.org
Therapy resistance is a major clinical problem in cancer medicine and crucial for disease
relapse and progression. Therefore, the clinical need to overcome it, particularly for …
relapse and progression. Therefore, the clinical need to overcome it, particularly for …
Nonoperative treatment of 15 benign esophageal perforations with self-expandable covered metal stents
A Fischer, O Thomusch, S Benz… - The Annals of thoracic …, 2006 - Elsevier
BACKGROUND: Spontaneous or iatrogenic esophageal perforations after endoscopic
procedures are potentially life-threatening events with a considerable mortality rate. The aim …
procedures are potentially life-threatening events with a considerable mortality rate. The aim …