Initial experience of 68Ga-PSMA PET/CT imaging in high-risk prostate cancer patients prior to radical prostatectomy

L Budäus, SR Leyh-Bannurah, G Salomon, U Michl… - European urology, 2016 - Elsevier
Prostate-specific membrane antigen (PSMA) overexpression theoretically enables targeting
of prostate cancer (PCa) metastases using gallium Ga 68 (68 Ga)–labeled PSMA ligands for …

Clinical utility of quantitative Gleason grading in prostate biopsies and prostatectomy specimens

G Sauter, S Steurer, TS Clauditz, T Krech, C Wittmer… - European urology, 2016 - Elsevier
Background Gleason grading is the strongest prognostic parameter in prostate cancer.
Gleason grading is categorized as Gleason≤ 6, 3+ 4, 4+ 3, 8, and 9–10, but there is …

Neurovascular structure-adjacent frozen-section examination (NeuroSAFE) increases nerve-sparing frequency and reduces positive surgical margins in open and …

T Schlomm, P Tennstedt, C Huxhold, T Steuber… - European urology, 2012 - Elsevier
BACKGROUND: Intraoperative frozen-section analysis allows real-time histologic
assessment of surgical margins (SMs) and identification of candidates for nerve-sparing …

Full functional-length urethral sphincter preservation during radical prostatectomy

T Schlomm, H Heinzer, T Steuber, G Salomon, O Engel… - European urology, 2011 - Elsevier
BACKGROUND: A key prerequisite for urinary continence after radical prostatectomy (RP) is
the functional length of the urethral sphincter and the stabilisation of its anatomic position …

Recurrent deletion of 3p13 targets multiple tumour suppressor genes and defines a distinct subgroup of aggressive ERG fusion‐positive prostate cancers

A Krohn, A Seidel, L Burkhardt… - The Journal of …, 2013 - Wiley Online Library
Deletion of 3p13 has been reported from about 20% of prostate cancers. The clinical
significance of this alteration and the tumour suppressor gene (s) driving the deletion remain …

Nerve distribution along the prostatic capsule

C Eichelberg, A Erbersdobler, U Michl, T Schlomm… - European urology, 2007 - Elsevier
OBJECTIVES: Recent literature describes indications for a more-complex course of fibres of
the neurovascular bundle (NVB), despite the widely held assumption that it is gathered at …

Nerve-sparing surgery technique, not the preservation of the neurovascular bundles, leads to improved long-term continence rates after radical prostatectomy

U Michl, P Tennstedt, L Feldmeier, P Mandel, SJ Oh… - European urology, 2016 - Elsevier
Background The effect of preservation of neurovascular bundles (NVBs) during radical
prostatectomy (RP) on continence remains controversial. Objective To analyze if the differing …

A validated strategy for side specific prediction of organ confined prostate cancer: a tool to select for nerve sparing radical prostatectomy

…, RP HENKE, UWE MICHL… - The Journal of …, 2001 - auajournals.org
Purpose: Nerve sparing radical prostatectomy for prostate cancer should be restricted to
patients who harbor tumors without capsular penetration. To our knowledge the selection …

Significant upgrading affects a third of men diagnosed with prostate cancer: predictive nomogram and internal validation

FKH CHUN, A Briganti, SF Shariat, M Graefen… - BJU …, 2006 - Wiley Online Library
OBJECTIVE To explore the rate of significant upgrading from biopsy to radical prostatectomy
(RP) specimens in a contemporary cohort, and to develop a prognostic model capable of …

A comparative study of robot‐assisted and open radical prostatectomy in 10 790 men treated by highly trained surgeons for both procedures

A Haese, S Knipper, H Isbarn, H Heinzer… - BJU …, 2019 - Wiley Online Library
Objective To compare oncological, functional and surgical outcomes of open retropubic
radical prostatectomy (ORP) vs robot‐assisted laparoscopic radical prostatectomy (RARP) …