Primate archaeology

M Haslam, A Hernandez-Aguilar, V Ling, S Carvalho… - Nature, 2009 - nature.com
All modern humans use tools to overcome limitations of our anatomy and to make difficult
tasks easier. However, if tool use is such an advantage, we may ask why it is not evolved to …

[HTML][HTML] The role of an anti-inflammatory diet in conjunction to COVID-19

V Ling, I Zabetakis - Diseases, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), otherwise known as
COVID-19, has challenged healthcare systems at an international level. COVID-19 …

[HTML][HTML] Imetelstat-mediated alterations in fatty acid metabolism to induce ferroptosis as a therapeutic strategy for acute myeloid leukemia

C Bruedigam, AH Porter, A Song, G Vroeg in de Wei… - Nature Cancer, 2023 - nature.com
Telomerase enables replicative immortality in most cancers including acute myeloid
leukemia (AML). Imetelstat is a first-in-class telomerase inhibitor with clinical efficacy in …

Targeting cell cycle and apoptosis to overcome chemotherapy resistance in acute myeloid leukemia

VY Ling, J Straube, W Godfrey, R Haldar… - Leukemia, 2023 - nature.com
Chemotherapy-resistant acute myeloid leukemia (AML), frequently driven by clonal
evolution, has a dismal prognosis. A genome-wide CRISPR knockout screen investigating …

The impact of age, NPM1mut, and FLT3ITD allelic ratio in patients with acute myeloid leukemia

J Straube, VY Ling, GR Hill… - Blood, The Journal of the …, 2018 - ashpublications.org
Acute myeloid leukemia (AML) is a heterogeneous disease for which genetic profiles dictate
clinical outcomes. Cytogenetic and molecular profiling in AML is a mandatory diagnostic and …

Jak2V617F and Dnmt3a loss cooperate to induce myelofibrosis through activated enhancer-driven inflammation

S Jacquelin, J Straube, L Cooper, T Vu… - Blood, The Journal …, 2018 - ashpublications.org
Myeloproliferative neoplasms (MPNs) are a group of blood cancers that arise following the
sequential acquisition of genetic lesions in hematopoietic stem and progenitor cells …

How unique is pure erythroid leukaemia? A retrospective analysis of seven cases and review of the literature

E Wong, V Ling, D Westerman, S Morgan… - Journal of Clinical …, 2015 - jcp.bmj.com
Aims Pure erythroid leukaemia (PEL) is a rare subtype of acute myeloid leukaemia (AML)
and its clinicopathological features are not well-defined. The aim of this study was to …

Development and evaluation of an educational game to support pharmacy students

S Nabhani, N Harrap, S Ishtiaq, V Ling… - Currents in Pharmacy …, 2020 - Elsevier
Abstract Introduction United Kingdom pharmacy students need to efficiently navigate the
British National Formulary (BNF), a standard medicines reference source.“Pharmacy …

[HTML][HTML] Hematopoietic stem and progenitor cell-restricted Cdx2 expression induces transformation to myelodysplasia and acute leukemia

T Vu, J Straube, AH Porter, M Bywater, A Song… - Nature …, 2020 - nature.com
The caudal-related homeobox transcription factor CDX2 is expressed in leukemic cells but
not during normal blood formation. Retroviral overexpression of Cdx2 induces AML in mice …

Clearing the way for new therapies in clonal hematopoiesis

VY Ling, SW Lane - Blood Advances, 2023 - ashpublications.org
In this issue of Blood Advances, Gustafsson et al examined the effect of an anti-CD45
antibody drug conjugate (ADC) on tissue-resident myeloid cells (TRM) in healthy and …